Search Results - Sabina Signoretti

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  1. 1

    Metastatic penile carcinoma associated with convergent gain-of-function mutations in NOTCH1 by Sabina Signoretti, Jon C. Aster

    Published in Human Pathology: Case Reports (2018-03-01)
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  2. 2

    Mitochondrial transporter expression patterns distinguish tumor from normal tissue and identify cancer subtypes with different survival and metabolism by Hartmut Wohlrab, Sabina Signoretti, Lucia E. Rameh, Derrick K. DeConti, Steen H. Hansen

    Published in Scientific Reports (2022-10-01)
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  3. 3

    Cell kinetic studies fail to identify sequentially proliferating progenitors as the major source of epithelial renewal in the adult murine prostate. by Jean-Christophe Pignon, Chiara Grisanzio, Ingrid Carvo, Lillian Werner, Meredith Regan, E Lynette Wilson, Sabina Signoretti

    Published in PLoS ONE (2015-01-01)
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  4. 4

    Regulation of HHLA2 expression in kidney cancer and myeloid cells by Tomonari Shigemura, Nahuel Perrot, Zimo Huang, Rupal S. Bhatt, Aseman Bagheri Sheshdeh, Nourhan El Ahmar, Fatme Ghandour, Sabina Signoretti, David F. McDermott, Gordon J. Freeman, Kathleen M. Mahoney

    Published in BMC Cancer (2023-10-01)
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  5. 5

    A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis by Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg, Massimo Loda

    Published in EMBO Molecular Medicine (2014-02-01)
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  6. 6

    A novel direct activator of AMPK inhibits prostate cancer growth by blocking lipogenesis by Giorgia Zadra, Cornelia Photopoulos, Svitlana Tyekucheva, Pedram Heidari, Qing Ping Weng, Giuseppe Fedele, Hong Liu, Natalia Scaglia, Carmen Priolo, Ewa Sicinska, Umar Mahmood, Sabina Signoretti, Neal Birnberg, Massimo Loda

    Published in EMBO Molecular Medicine (2014-10-01)
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  7. 7

    Correction to: Outcomes based on plasma biomarkers in METEOR, a randomized phase 3 trial of cabozantinib vs everolimus in advanced renal cell carcinoma by Thomas Powles, Toni K. Choueiri, Robert J. Motzer, Eric Jonasch, Sumanta Pal, Nizar M. Tannir, Sabina Signoretti, Rajesh Kaldate, Christian Scheffold, Evelyn Wang, Dana T. Aftab, Bernard Escudier, Daniel J. George

    Published in BMC Cancer (2021-09-01)
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  8. 8

    Mechanisms of acquired resistance to rapalogs in metastatic renal cell carcinoma. by Lana Hamieh, Toni K Choueiri, Barbara Ogórek, Damir Khabibullin, Daniel Rosebrock, Dimitri Livitz, Andre Fay, Jean-Christophe Pignon, David F McDermott, Neeraj Agarwal, Wenhua Gao, Sabina Signoretti, David J Kwiatkowski

    Published in PLoS Genetics (2018-09-01)
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  9. 9

    Long-term outcomes with nivolumab plus ipilimumab versus sunitinib in first-line treatment of patients with advanced sarcomatoid renal cell carcinoma by Chung-Wei Lee, Thomas Powles, Sabina Signoretti, Sumanta K Pal, Toni K Choueiri, Brian I Rini, Saby George, Robert J Motzer, Frede Donskov, Scott S Tykodi, Nizar M Tannir, Saurabh Gupta, Ruiyun Jiang

    Published in Journal for ImmunoTherapy of Cancer (2022-12-01)
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  10. 10

    Resistance of renal cell carcinoma to sorafenib is mediated by potentially reversible gene expression. by Liang Zhang, Manoj Bhasin, Rachel Schor-Bardach, Xiaoen Wang, Michael P Collins, David Panka, Prabhakar Putheti, Sabina Signoretti, David C Alsop, Towia Libermann, Michael B Atkins, James W Mier, S Nahum Goldberg, Rupal S Bhatt

    Published in PLoS ONE (2011-04-01)
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  11. 11

    Immune dysfunction revealed by digital spatial profiling of immuno-oncology markers in progressive stages of renal cell carcinoma and in brain metastases by Wei Wei, Michael Hurwitz, Sabina Signoretti, Lucia Jilaveanu, Toni K Choueiri, David L Rimm, Adebowale Adeniran, Sandra Martínez, Harriet M Kluger, David A Schoenfeld, Myrto Moutafi, Dijana Djureinovic, Ross D Merkin, David A Braun, Fabio Parisi

    Published in Journal for ImmunoTherapy of Cancer (2023-08-01)
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  12. 12

    1017 SLAMF7+ CD8+ exhausted T cell-specific gene signature is associated with resistance to PD1 blockade in renal cell carcinoma by Michael Hurwitz, Elizabeth Plimack, Jeffrey Sosman, Sabina Signoretti, David F McDermott, Michael B Atkins, Naomi B Haas, Hans Hammers, Nicholas Schindler, Opeyemi A Jegede, Catherine J Wu, David Braun, Miya Hugaboom, Kelly Street, Neil Ruthen, Lena Wirth

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  13. 13

    442 CAIX targeted CAR-T cells exhibited antitumor efficacy on renal cell carcinoma (RCC) patient derived organotypic tumor spheroids (PDOTS) by Sabina Signoretti, Toni K Choueiri, Cloud Paweletz, Kun Huang, Yufei Wang, Gordon Freeman, Alicia Buck, Gabriella Kastrunes, Marion Grimaud, Atef Fayed, Luann Zerefa, Brandon Piel, Elena Ivanova, Miriam Ficial, Jon Wee, David Barbie, Wayne Marasco, Andras-Gabor Miklosi, Tran Thai, Ming-Ru Wu

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  14. 14

    Regulation of neuroendocrine plasticity by the RNA-binding protein ZFP36L1 by Hsiao-Yun Chen, Yavuz T. Durmaz, Yixiang Li, Amin H. Sabet, Amir Vajdi, Thomas Denize, Emily Walton, Yasmin Nabil Laimon, John G. Doench, Navin R. Mahadevan, Julie-Aurore Losman, David A. Barbie, Michael Y. Tolstorukov, Charles M. Rudin, Triparna Sen, Sabina Signoretti, Matthew G. Oser

    Published in Nature Communications (2022-08-01)
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  15. 15

    Immune-restoring CAR-T cells display antitumor activity and reverse immunosuppressive TME in a humanized ccRCC mouse model by Yufei Wang, Jae-Won Cho, Gabriella Kastrunes, Alicia Buck, Cecile Razimbaud, Aedin C. Culhane, Jiusong Sun, David A. Braun, Toni K. Choueiri, Catherine J. Wu, Kristen Jones, Quang-De Nguyen, Zhu Zhu, Kevin Wei, Quan Zhu, Sabina Signoretti, Gordon J. Freeman, Martin Hemberg, Wayne A. Marasco

    Published in iScience (2024-02-01)
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  16. 16

    Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development. by Krinio Giannikou, Izabela A Malinowska, Trevor J Pugh, Rachel Yan, Yuen-Yi Tseng, Coyin Oh, Jaegil Kim, Magdalena E Tyburczy, Yvonne Chekaluk, Yang Liu, Nicola Alesi, Geraldine A Finlay, Chin-Lee Wu, Sabina Signoretti, Matthew Meyerson, Gad Getz, Jesse S Boehm, Elizabeth P Henske, David J Kwiatkowski

    Published in PLoS Genetics (2016-08-01)
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  17. 17

    Identification of ALK gene alterations in urothelial carcinoma. by Joaquim Bellmunt, Shamini Selvarajah, Scott Rodig, Marta Salido, Silvia de Muga, Irmgard Costa, Beatriz Bellosillo, Lillian Werner, Stephanie Mullane, André P Fay, Robert O'Brien, Jordi Barretina, André E Minoche, Sabina Signoretti, Clara Montagut, Heinz Himmelbauer, David M Berman, Philip Kantoff, Toni K Choueiri, Jonathan E Rosenberg

    Published in PLoS ONE (2014-01-01)
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  18. 18

    1511 Pan-tumor harmonization of pathologic response assessment for standardized data collection in neoadjuvant IO trials (PATHdata): Interim analysis of a multi-institutional repro... by Xiaowei Xu, Hao Wang, Michael Tetzlaff, James Ziai, Sabina Signoretti, Ashley Cimino-Mathews, Tricia Cottrell, Janis M Taube, Annikka Weissferdt, Richard A Scolyer, Pierre-Olivier Fiset, Jaime Rodriguez-Canales, Lynette M Sholl, Julie S Deutsch, Krista Chen, Carlos E de Andrea, Christine Orr, Salgado Roberto, Christian Schurch, Raja Seethala, Alexander S Baras

    Published in Journal for ImmunoTherapy of Cancer (2023-11-01)
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  19. 19

    Phase II study of nivolumab and salvage nivolumab/ipilimumab in treatment-naïve patients with advanced non-clear cell renal cell carcinoma (HCRN GU16-260-Cohort B) by Alessia Cimadamore, Michael Hurwitz, Mark Stein, Sabina Signoretti, Jeffrey A Sosman, David F McDermott, Michael B Atkins, Naomi B Haas, Elizabeth R Plimack, Hans Hammers, Mehmet A Bilen, Moshe C Ornstein, David Einstein, Opeyemi A Jegede, Robert Alter, David J Peace, Thomas Denize, Catherine J Wu, David Braun, Paul J Catalano

    Published in Journal for ImmunoTherapy of Cancer (2023-03-01)
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  20. 20

    Prognostic significance and immune correlates of CD73 expression in renal cell carcinoma by Neeraj Agarwal, Sabina Signoretti, David F McDermott, Toni K Choueiri, Wanling Xie, John A Steinharter, Nieves Martinez-Chanza, Bradley A McGregor, Lauren C Harshman, Abhishek Tripathi, Xiao X Wei, Edwin Lin, Abdallah Flaifel, Emily N Stern Gatof, Gabrielle Bouchard, Justin H Fleischer, Connor Gray, Charlene Mantia, Linda Thompson, Marios Giannakis

    Published in Journal for ImmunoTherapy of Cancer (2020-10-01)
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