Search Results - Simon P Fletcher
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Circulating HBsAg-specific B cells are partially rescued in chronically HBV-infected patients with functional cure by Shuqin Gu, Libo Tang, Ling Guo, Chunxiu Zhong, Xin Fu, Guofu Ye, Shihong Zhong, Xiaoyi Li, Chunhua Wen, Yang Zhou, Jinling Wei, Haitao Chen, Nikolai Novikov, Simon P. Fletcher, M. Anthony Moody, Jinlin Hou, Yongyin Li
Published in Emerging Microbes and Infections (2024-12-01)Get full text
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Intrahepatic quantification of HBV antigens in chronic hepatitis B reveals heterogeneity and treatment-mediated reductions in HBV core-positive cells by Abhishek Aggarwal, Pamela M. Odorizzi, Jens Brodbeck, Nicholas van Buuren, Christina Moon, Silvia Chang, MaryVic Adona, Silpa Suthram, Vithika Suri, Torsten Trowe, Scott Turner, Patrick Marcellin, Maria Buti, Anuj Gaggar, Simon P. Fletcher, Lauri Diehl, Becket Feierbach, Scott Balsitis
Published in JHEP Reports (2023-04-01)Get full text
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Hepatitis D virus infection triggers CXCL9-11 upregulation in hepatocytes and liver infiltration of CXCR3+ CD4 T cells by Jan-Hendrik Bockmann, Lena Allweiss, Annika Volmari, David da Fonseca Araújo, Matin Kohsar, Anastasia Hyrina, Janine Kah, Zhijuan Song, Josolyn Chan, Katja Giersch, Tassilo Volz, Marc Lütgehetmann, Jeffrey J. Wallin, Dmitry Manuilov, Meghan M. Holdorf, Simon P. Fletcher, Ansgar W. Lohse, Antonio Bertoletti, Julian Schulze zur Wiesch, Maura Dandri
Published in JHEP Reports (2025-03-01)Get full text
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Identification and engineering of potent bispecific antibodies that protect against herpes simplex virus recurrent disease by Chingwei V. Lee, Hector Viadiu, Apurva Kalamkar, David I. Bernstein, Andrew Pae, Xinchao Yu, Sylvia Wong, Fernando J. Bravo, Sheng Ding, Elbert Seto, Magdeleine Hung, Yu Yu, Weimei Xing, Giuseppe A. Papalia, Wei Kan, Brian Carr, Majlinda Thomas, Leah Tong, Priyanka Desai, Nadine Jarrousse, Alexandre Mercier, Meghan M. Holdorf, Simon P. Fletcher, Emma Abernathy
Published in Cell Reports (2025-08-01)Get full text
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A highly selective TCR-mimic antibody reveals unexpected mechanisms of HBV peptide-MHC recognition and previously unknown target biology by Shahzada Khan, Jeremy Lum, Heather Stephenson, Pawan Bir Kohli, David Mortenson, Dhivya Ramakrishnan, Magdeleine Hung, Sheng Ding, Elbert Seto, Sabrina Lu, Randy Yen, Debi Jin, Brian Lee, Sheila Clancy, Nicole Schirle Oakdale, Nikolai Novikov, Don Kang, Ruidong Li, David Pan, Rutwij Dave, Eric Lansdon, Simon P Fletcher, Abhishek V. Garg, Nathan Thomsen, Scott Balsitis
Published in mAbs (2025-12-01)Get full text
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Safety, pharmacodynamics, and antiviral activity of selgantolimod in viremic patients with chronic hepatitis B virus infection by Harry L. Janssen, Young-Suk Lim, Hyung Joon Kim, Leonard Sowah, Cheng-Hao Tseng, Carla S. Coffin, Magdy Elkhashab, Sang Hoon Ahn, Anh-Hoa Nguyen, Diana Chen, Jeffrey J. Wallin, Simon P. Fletcher, Circe McDonald, Jenny C. Yang, Anuj Gaggar, Diana M. Brainard, Scott Fung, Yoon Jun Kim, Jia-Horng Kao, Wan-Long Chuang, Anna E. Brooks, P. Rod Dunbar
Published in JHEP Reports (2024-02-01)Get full text
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Oral dosing of the nucleoside analog obeldesivir is efficacious against RSV infection in African green monkeys by Jared Pitts, J. Lizbeth Reyes Zamora, Savrina Manhas, Thomas Aeschbacher, Josolyn Chan, Vincent Cutillas, Varsha Nair, Nicholas C. Riola, Arya Vijjapurapu, Meghan S. Vermillion, Stacey Eng, Christopher Richards, Dong Han, Jason K. Perry, Subhra Chaudhuri, Szu-Wen Liu, Clarissa Martinez, Nadine Peinovich, Kai-Hui Sun, Arthur Cai, Ross Martin, Jasmine Moshiri, Charlotte Hedskog, Darius Babusis, Dustin S. Siegel, Rao Kalla, Vasanthi Avadhanula, Pedro A. Piedra, Kim Stobbelaar, Peter L. Delputte, Caleb Marceau, Roberto Mateo, Evguenia Maiorova, Hongmei Mo, Raju Subramanian, Richard L. Mackman, Tomas Cihlar, Simon P. Fletcher, John P. Bilello
Published in Nature Communications (2025-07-01)Get full text
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