Search Results - Simone Kunzelmann
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Discovering covalent cyclic peptide inhibitors of peptidyl arginine deiminase 4 (PADI4) using mRNA-display with a genetically encoded electrophilic warhead by Isabel R. Mathiesen, Ewen D. D. Calder, Simone Kunzelmann, Louise J. Walport
Published in Communications Chemistry (2024-12-01)Get full text
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Structural characterisation of the Chaetomium thermophilum Chl1 helicase. by Zuzana Hodáková, Andrea Nans, Simone Kunzelmann, Shahid Mehmood, Ian Taylor, Frank Uhlmann, Peter Cherepanov, Martin R Singleton
Published in PLoS ONE (2021-01-01)Get full text
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Activation loop phosphorylation and cGMP saturation of PKG regulate egress of malaria parasites. by Konstantinos Koussis, Silvia Haase, Chrislaine Withers-Martinez, Helen R Flynn, Simone Kunzelmann, Evangelos Christodoulou, Fairouz Ibrahim, Mark Skehel, David A Baker, Michael J Blackman
Published in PLoS Pathogens (2024-06-01)Get full text
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N4BP1 functions as a dimerization-dependent linear ubiquitin reader which regulates TNF signalling by Katarzyna W. Kliza, Wei Song, Irene Pinzuti, Simone Schaubeck, Simone Kunzelmann, David Kuntin, Arianna Fornili, Alessandro Pandini, Kay Hofmann, James A. Garnett, Benjamin Stieglitz, Koraljka Husnjak
Published in Cell Death Discovery (2024-04-01)Get full text
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WNK1-dependent water influx is required for CD4+ T cell activation and T cell-dependent antibody responses by Joshua Biggs O’May, Lesley Vanes, Leonard L. de Boer, David A. Lewis, Harald Hartweger, Simone Kunzelmann, Darryl Hayward, Miriam Llorian, Robert Köchl, Victor L. J. Tybulewicz
Published in Nature Communications (2025-02-01)Get full text
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Platform-directed allostery and quaternary structure dynamics of SAMHD1 catalysis by Oliver J. Acton, Devon Sheppard, Simone Kunzelmann, Sarah J. Caswell, Andrea Nans, Ailidh J. O. Burgess, Geoff Kelly, Elizabeth R. Morris, Peter B. Rosenthal, Ian A. Taylor
Published in Nature Communications (2024-05-01)Get full text
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Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction. by Laurence H Arnold, Harriet C T Groom, Simone Kunzelmann, David Schwefel, Sarah J Caswell, Paula Ordonez, Melanie C Mann, Sabrina Rueschenbaum, David C Goldstone, Simon Pennell, Steven A Howell, Jonathan P Stoye, Michelle Webb, Ian A Taylor, Kate N Bishop
Published in PLoS Pathogens (2015-10-01)Get full text
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