檢索結果 - Tim Vanmierlo

Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation 由 Stefan Brocke, Paul M. Epstein, Robert Nelson, Tim Vanmierlo, Tim Vanmierlo

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Novel insights in phosphodiesterase 4 subtype inhibition to target neuroinflammation and stimulate remyelination 由 Melissa Schepers, Tim Vanmierlo

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Insights from an academic endeavor into central nervous system drug discovery 由 Lieve van Veggel, An M. Voets, Tim Vanmierlo, Rudy Schreiber

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Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720 由 Alessandra Roggeri, Guendalina Olivero, Cesare Usai, Tim Vanmierlo, Anna Pittaluga

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Targeting Phosphodiesterases—Towards a Tailor-Made Approach in Multiple Sclerosis Treatment 由 Melissa Schepers, Melissa Schepers, Assia Tiane, Assia Tiane, Dean Paes, Dean Paes, Selien Sanchez, Ben Rombaut, Elisabeth Piccart, Elisabeth Piccart, Bart P. F. Rutten, Bert Brône, Niels Hellings, Jos Prickaerts, Tim Vanmierlo, Tim Vanmierlo

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Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment? 由 Ellis Nelissen, Melissa Schepers, Laura Ponsaerts, Sébastien Foulquier, Annelies Bronckaers, Tim Vanmierlo, Peter Sandner, Jos Prickaerts

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Liver X receptors: A therapeutic target in demyelinating disorders 由 Jule Richartz, Sammie C. Yam, Na Zhan, Melissa Schepers, Assia Tiane, Monique T. Mulder, Inez Wens, Tim Vanmierlo

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Neuroinflammation in Ischemic Stroke: Inhibition of cAMP-Specific Phosphodiesterases (PDEs) to the Rescue 由 Laura Ponsaerts, Lotte Alders, Melissa Schepers, Rúbia Maria Weffort de Oliveira, Jos Prickaerts, Tim Vanmierlo, Annelies Bronckaers

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PDE5 inhibition improves object memory in standard housed rats but not in rats housed in an enriched environment: implications for memory models? 由 Sven Akkerman, Jos Prickaerts, Ann K Bruder, Kevin H M Wolfs, Jochen De Vry, Tim Vanmierlo, Arjan Blokland

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From OPC to Oligodendrocyte: An Epigenetic Journey 由 Assia Tiane, Melissa Schepers, Ben Rombaut, Raymond Hupperts, Jos Prickaerts, Niels Hellings, Daniel van den Hove, Tim Vanmierlo

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Sex differentially affects pro-inflammatory cell subsets in adipose tissue depots in a diet induced obesity model 由 Lisa T. Schuetz, Gayel Duran, Paulien Baeten, Daphne Lintsen, Doryssa Hermans, Sarah Chenine, Janne Verreycken, Tim Vanmierlo, Kristiaan Wouters, Bieke Broux

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Impact on murine neurodevelopment of early-life exposure to airborne ultrafine carbon nanoparticles 由 Kenneth Vanbrabant, Leen Rasking, Maartje Vangeneugden, Hannelore Bové, Marcel Ameloot, Tim Vanmierlo, Roel P. F. Schins, Flemming R. Cassee, Michelle Plusquin

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Low-Density Lipoprotein Receptor Deficiency Attenuates Neuroinflammation through the Induction of Apolipoprotein E 由 Jo Mailleux, Silke Timmermans, Katherine Nelissen, Jasmine Vanmol, Tim Vanmierlo, Jack van Horssen, Jeroen F. J. Bogie, Jerome J. A. Hendriks

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Generation of a ST3GAL3 null mutant induced pluripotent stem cell (iPSC) line (UKWMPi002-A-3) by CRISPR/Cas9 genome editing 由 David Diouf, Maria Rosaria Vitale, Johanna Eva Maria Zöller, Ana-Magdalena Pineau, Eva Klopocki, Catharina Hamann, Georg Christoph Ziegler, Tim Vanmierlo, Daniel Van den Hove, Klaus-Peter Lesch

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Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition 由 Melissa Schepers, Sven Hendrix, Femke Mussen, Elise van Breedam, Peter Ponsaerts, Stefanie Lemmens, Niels Hellings, Roberta Ricciarelli, Ernesto Fedele, Olga Bruno, Chiara Brullo, Jos Prickaerts, Jana Van Broeckhoven, Tim Vanmierlo

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Cerebral microvascular endothelial cell-derived extracellular vesicles regulate blood − brain barrier function 由 Baharak Hosseinkhani, Gayel Duran, Cindy Hoeks, Doryssa Hermans, Melissa Schepers, Paulien Baeten, Joren Poelmans, Britt Coenen, Kübra Bekar, Isabel Pintelon, Jean-Pierre Timmermans, Tim Vanmierlo, Luc Michiels, Niels Hellings, Bieke Broux

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Generation of induced pluripotent stem cell (iPSC) lines carrying a heterozygous (UKWMPi002-A-1) and null mutant knockout (UKWMPi002-A-2) of Cadherin 13 associated with neurodevelo... 由 Maria Rosaria Vitale, Johanna Eva Maria Zöller, Charline Jansch, Anna Janz, Frank Edenhofer, Eva Klopocki, Daniel van den Hove, Tim Vanmierlo, Olga Rivero, Nael Nadif Kasri, Georg Christoph Ziegler, Klaus-Peter Lesch

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24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer’s Disease 由 Nikita Martens, Melissa Schepers, Na Zhan, Frank Leijten, Gardi Voortman, Assia Tiane, Ben Rombaut, Janne Poisquet, Nienke van de Sande, Anja Kerksiek, Folkert Kuipers, Johan W. Jonker, Hongbing Liu, Dieter Lütjohann, Tim Vanmierlo, Monique T. Mulder

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Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice 由 Ben Rombaut, Melissa Schepers, Assia Tiane, Femke Mussen, Lisa Koole, Sofie Kessels, Chloë Trippaers, Ruben Jacobs, Kristiaan Wouters, Emily Willems, Lieve van Veggel, Philippos Koulousakis, Dorien Deluyker, Virginie Bito, Jos Prickaerts, Inez Wens, Bert Brône, Daniel L. A. van den Hove, Tim Vanmierlo

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Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood–brain barrier impairment 由 Narek Manukjan, Daria Majcher, Peter Leenders, Florian Caiment, Marcel van Herwijnen, Hubert J. Smeets, Ernst Suidgeest, Louise van der Weerd, Tim Vanmierlo, Jacobus F. A. Jansen, Walter H. Backes, Robert J. van Oostenbrugge, Julie Staals, Daniel Fulton, Zubair Ahmed, W. Matthijs Blankesteijn, Sébastien Foulquier

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