Search Results - Timothy P. Hickling

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  1. 1

    The Role of Aggregates of Therapeutic Protein Products in Immunogenicity: An Evaluation by Mathematical Modeling by Liusong Yin, Xiaoying Chen, Abhinav Tiwari, Paolo Vicini, Timothy P. Hickling

    Published in Journal of Immunology Research (2015-01-01)
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  2. 2

    Expanding the MAPPs Assay to Accommodate MHC-II Pan Receptors for Improved Predictability of Potential T Cell Epitopes by Katharina Hartman, Guido Steiner, Michel Siegel, Cary M. Looney, Timothy P. Hickling, Katharine Bray-French, Sebastian Springer, Céline Marban-Doran, Axel Ducret

    Published in Biology (2023-09-01)
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  3. 3

    CD8+ T Lymphocyte Epitopes From The Herpes Simplex Virus Type 2 ICP27, VP22 and VP13/14 Proteins To Facilitate Vaccine Design And Characterization by Rebecca J. Platt, Tansi Khodai, Tim J. Townend, Helen H. Bright, Paul Cockle, Luis Perez-Tosar, Rob Webster, Brian Champion, Timothy P. Hickling, Fareed Mirza

    Published in Cells (2013-01-01)
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  4. 4

    HLAIIPred: cross-attention mechanism for modeling the interaction of HLA class II molecules with peptides by Mojtaba Haghighatlari, Nicholas Marze, Robert Seward, Andrew Ciarla, Rachel Hindin, Jennifer Calderini, Benjamin Keenan, Santosh Dhule, Sarah Hall-Swan, Timothy P. Hickling, Eric Bennett, Brajesh Rai, Sophie Tourdot

    Published in Communications Biology (2025-07-01)
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  5. 5

    Validation of a Dendritic Cell and CD4+ T Cell Restimulation Assay Contributing to the Immunogenicity Risk Evaluation of Biotherapeutics by Michel Siegel, Guido Steiner, Linnea C. Franssen, Francesca Carratu, James Herron, Katharina Hartman, Cary M. Looney, Axel Ducret, Katharine Bray-French, Olivier Rohr, Timothy P. Hickling, Noel Smith, Céline Marban-Doran

    Published in Pharmaceutics (2022-12-01)
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  6. 6

    Internalization of therapeutic antibodies into dendritic cells as a risk factor for immunogenicity by Michel Siegel, Anna-Lena Bolender, Axel Ducret, Johannes Fraidling, Katharina Hartman, Cary M. Looney, Olivier Rohr, Olivier Rohr, Timothy P. Hickling, Hubert Kettenberger, Martin Lechmann, Céline Marban-Doran, Thomas E. Kraft

    Published in Frontiers in Immunology (2024-08-01)
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  7. 7

    Development and characterization of dendritic cell internalization and activation assays contributing to the immunogenicity risk evaluation of biotherapeutics by Michel Siegel, Aman Padamsey, Anna-Lena Bolender, Patrick Hargreaves, Johannes Fraidling, Axel Ducret, Katharina Hartman, Cary M. Looney, Cristina Bertinetti-Lapatki, Olivier Rohr, Olivier Rohr, Timothy P. Hickling, Thomas E. Kraft, Céline Marban-Doran

    Published in Frontiers in Immunology (2024-08-01)
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  8. 8

    A Quantitative Systems Pharmacology Consortium Approach to Managing Immunogenicity of Therapeutic Proteins by Andrzej M. Kierzek, Timothy P. Hickling, Isabel Figueroa, J. Cory Kalvass, Marjoleen Nijsen, Krithika Mohan, Geertruida M. Veldman, Akihiro Yamada, Hiroyuki Sayama, Sachiko Yokoo, Abhishek Gulati, Renu S. Dhanikula, Jochem Gokemeijer, Tarek A. Leil, Craig J. Thalhauser, Mario Giorgi, Maciej J. Swat, Vijayalakshmi Chelliah, Ben G. Small, Neil Benson, Michael Walker, Kapil Gadkar, Valerie Quarmby, Rong Deng, Andrea Ferrante, Gemma L. Dickinson, Jan‐Stefan Van Der Walt, Lian Zhou, Xiaoying Chen, Hannah M. Jones, Jatin Narula, Sophie Tourdot, Thierry Lavé, Benjamin Ribba, Piet H. van derGraaf

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