Search Results - Ultan McDermott

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  1. 1

    Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties. by Michael P Menden, Francesco Iorio, Mathew Garnett, Ultan McDermott, Cyril H Benes, Pedro J Ballester, Julio Saez-Rodriguez

    Published in PLoS ONE (2013-01-01)
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  2. 2

    A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency by Sebastian Lukasiak, Alex Kalinka, Nikhil Gupta, Angelos Papadopoulos, Khalid Saeed, Ultan McDermott, Gregory James Hannon, Douglas Ross-Thriepland, David Walter

    Published in BMC Genomics (2025-02-01)
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  3. 3

    Targeting Acid Ceramidase to Improve the Radiosensitivity of Rectal Cancer by Rachael E. Clifford, Naren Govindarajah, David Bowden, Paul Sutton, Mark Glenn, Mahnaz Darvish-Damavandi, Simon Buczacki, Ultan McDermott, Zdzislaw Szulc, Besim Ogretmen, Jason L. Parsons, Dale Vimalachandran

    Published in Cells (2020-12-01)
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  4. 4

    Combinations of PARP Inhibitors with Temozolomide Drive PARP1 Trapping and Apoptosis in Ewing's Sarcoma. by Sonja J Gill, Jon Travers, Irina Pshenichnaya, Fiona A Kogera, Syd Barthorpe, Tatiana Mironenko, Laura Richardson, Cyril H Benes, Michael R Stratton, Ultan McDermott, Stephen P Jackson, Mathew J Garnett

    Published in PLoS ONE (2015-01-01)
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  5. 5

    Integrative ensemble modelling of cetuximab sensitivity in colorectal cancer patient-derived xenografts by Umberto Perron, Elena Grassi, Aikaterini Chatzipli, Marco Viviani, Emre Karakoc, Lucia Trastulla, Lorenzo M. Brochier, Claudio Isella, Eugenia R. Zanella, Hagen Klett, Ivan Molineris, Julia Schueler, Manel Esteller, Enzo Medico, Nathalie Conte, Ultan McDermott, Livio Trusolino, Andrea Bertotti, Francesco Iorio

    Published in Nature Communications (2024-11-01)
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  6. 6

    A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia by Konstantinos Tzelepis, Hiroko Koike-Yusa, Etienne De Braekeleer, Yilong Li, Emmanouil Metzakopian, Oliver M. Dovey, Annalisa Mupo, Vera Grinkevich, Meng Li, Milena Mazan, Malgorzata Gozdecka, Shuhei Ohnishi, Jonathan Cooper, Miten Patel, Thomas McKerrell, Bin Chen, Ana Filipa Domingues, Paolo Gallipoli, Sarah Teichmann, Hannes Ponstingl, Ultan McDermott, Julio Saez-Rodriguez, Brian J.P. Huntly, Francesco Iorio, Cristina Pina, George S. Vassiliou, Kosuke Yusa

    Published in Cell Reports (2016-10-01)
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  7. 7

    Genome-wide CRISPR screens identify the YAP/TEAD axis as a driver of persister cells in EGFR mutant lung cancer by Matthias Pfeifer, Jonathan S. Brammeld, Stacey Price, James Pilling, Deepa Bhavsar, Anca Farcas, Jessica Bateson, Anjana Sundarrajan, Ricardo J. Miragaia, Nin Guan, Stephanie Arnold, Laiba Tariq, Michael Grondine, Sarah Talbot, Maria Lisa Guerriero, Daniel J. O’Neill, Jamie Young, Carlos Company, Shanade Dunn, Hannah Thorpe, Matthew J. Martin, Kimberly Maratea, Daniel Barrell, Miika Ahdesmaki, Jerome T. Mettetal, Functional Genomics Centre, James Brownell, Ultan McDermott

    Published in Communications Biology (2024-04-01)
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  8. 8

    Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells by Krishna Kalyan Kolluri, Constantine Alifrangis, Neelam Kumar, Yuki Ishii, Stacey Price, Magali Michaut, Steven Williams, Syd Barthorpe, Howard Lightfoot, Sara Busacca, Annabel Sharkey, Zhenqiang Yuan, Elizabeth K Sage, Sabarinath Vallath, John Le Quesne, David A Tice, Doraid Alrifai, Sylvia von Karstedt, Antonella Montinaro, Naomi Guppy, David A Waller, Apostolos Nakas, Robert Good, Alan Holmes, Henning Walczak, Dean A Fennell, Mathew Garnett, Francesco Iorio, Lodewyk Wessels, Ultan McDermott, Samuel M Janes

    Published in eLife (2018-01-01)
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  9. 9

    Identification and validation of a machine learning model of complete response to radiation in rectal cancer reveals immune infiltrate and TGFβ as key predictorsResearch in context... by Enric Domingo, Sanjay Rathee, Andrew Blake, Leslie Samuel, Graeme Murray, David Sebag-Montefiore, Simon Gollins, Nicholas West, Rubina Begum, Susan Richman, Phil Quirke, Keara Redmond, Aikaterini Chatzipli, Alessandro Barberis, Sylvana Hassanieh, Umair Mahmood, Michael Youdell, Ultan McDermott, Viktor Koelzer, Simon Leedham, Ian Tomlinson, Philip Dunne, Francesca M. Buffa, Timothy S. Maughan, Andrew Blake, Francesca Buffa, Enric Domingo, Geoffrey Higgins, Christopher Holmes, Viktor Koelzer, Simon Leedham, Timothy Maughan, Gillies McKenna, James Robineau, Ian Tomlinson, Michael Youdell, Philip Quirke, Susan Richman, David Sebag-Montefiore, Matthew Seymour, Nicholas West, Philip Dunne, Richard Kennedy, Mark Lawler, Keara Redmond, Manuel Salto-Tellez, Peter Campbell, Aikaterini Chatzipli, Claire Hardy, Ultan McDermott, Simon Bach, Andrew Beggs, Jean-Baptiste Cazier, Gary Middleton, Dion Morton, Celina Whalley, Louise Brown, Richard Kaplan, Graeme Murray, Richard Wilson, Richard Adams, Richard Sullivan, Leslie Samuel, Paul Harkin, Steven Walker, Jim Hill, Chieh-Hsi Wu, Dennis Horgan

    Published in EBioMedicine (2024-08-01)
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