Search Results - Xiuning Le
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Targeting the MET gene: unveiling therapeutic opportunities in immunotherapy within the tumor immune microenvironment of non-small cell lung cancer by Lisha Ye, Wenjing Wang, Huihui Li, Yongling Ji, Xiuning Le, Xiaoling Xu
Published in Therapeutic Advances in Medical Oncology (2024-10-01)Get full text
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Progress and challenges of artificial intelligence in lung cancer clinical translation by Erjia Zhu, Amgad Muneer, Jianjun Zhang, Yang Xia, Xiaomeng Li, Caicun Zhou, John V. Heymach, Jia Wu, Xiuning Le
Published in npj Precision Oncology (2025-07-01)Get full text
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AI in drug discovery and its clinical relevance by Rizwan Qureshi, Muhammad Irfan, Taimoor Muzaffar Gondal, Sheheryar Khan, Jia Wu, Muhammad Usman Hadi, John Heymach, Xiuning Le, Hong Yan, Tanvir Alam
Published in Heliyon (2023-07-01)Get full text
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Ensartinib for advanced or metastatic non-small-cell lung cancer with MET exon 14 skipping mutations (EMBRACE): a multi-center, single-arm, phase 2 trialResearch in context by Yang Xia, Panwen Tian, Mo Zhou, Jun Zhao, Yang Jin, Zhiyuan Guo, Xiuzhen Li, Weina Lu, Da Miao, Yuefei Lu, Wanting Xu, Yongchang Zhang, Xiuning Le, Wen Li
Published in EClinicalMedicine (2025-03-01)Get full text
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Molecular landscape of ERBB2 alterations in 3000 advanced NSCLC patients by Lingzhi Hong, Sonia Patel, Leylah M. Drusbosky, Yuanyuan Xiong, Rongrong Chen, Ruixuan Geng, Simon Heeke, Monique Nilsson, Jia Wu, John V. Heymach, Yingyi Wang, Jianjun Zhang, Xiuning Le
Published in npj Precision Oncology (2024-10-01)Get full text
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Personal history of cancer as a risk factor for second primary lung cancer: Implications for lung cancer screening by Sara Nofal, Jiangong Niu, Paul Resong, Jeff Jin, Kelly W. Merriman, Xiuning Le, Hormuzd Katki, John Heymach, Mara B. Antonoff, Edwin Ostrin, Jia Wu, Jianjun Zhang, Iakovos Toumazis
Published in Cancer Medicine (2024-03-01)Get full text
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283 Safety and efficacy signals in the complete phase I study of live biotherapeutic MRx0518 in combination with pembrolizumab in patients refractory to immune checkpoint inhibitor... by Alexander Stevenson, Jianjun Gao, Pavlos Msaouel, Nizar Tannir, Mehmet Altan, Shi-Ming Tu, Michael Chisamore, Matthew Campbell, George Blumenschein, Xiuning Le, Frank Mott, Amishi Shah, Jordi Rodon, Imke Mulder
Published in Journal for ImmunoTherapy of Cancer (2020-11-01)Article -
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Case report: Molecular profiling facilitates the diagnosis of a challenging case of lung cancer with choriocarcinoma features by Hui Li, Hui Li, Xin Hu, Matthew S. Ning, Gregory N. Fuller, John M. Stewart, Jared C. Gilliam, Jia Wu, Jia Wu, Xiuning Le, Ara A. Vaporciyan, J. Jack Lee, Don L. Gibbons, Don L. Gibbons, John V. Heymach, Andrew Futreal, Jianjun Zhang, Jianjun Zhang
Published in Frontiers in Oncology (2024-03-01)Get full text
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754 TIGIT-PVR is a key immune checkpoint and therapeutic target in HPV-positive head and neck squamous cell carcinomas by Linghua Wang, Jeffrey Myers, Michelle Williams, Alexandre Reuben, Michael Curran, Neil Gross, Diana Bell, Xiuning Le, Maura Gillison, Minghao Dang, Amit Agrawal, Stephen Lai, Ryan Goepfert, Qianyun Luo, Ravaen Slay, Venkatesh Hegde, Weihong Xiao, Keiko Akagi, Joseph Fresquez, Kathrina Marcelo, Pragya Sinha, Ananta Yanamandra, Edwin Parra Cuentas, Jagannadha Sastry
Published in Journal for ImmunoTherapy of Cancer (2021-11-01)Article -
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277 Combined neoadjuvant chemo-immunotherapy therapy achieves superior downstaging of resectable non-small cell lung cancer as compared to chemotherapy, mono or dual immunotherapy... by Heather Lin, Charles Lu, Mehmet Altan, Apar Pataer, Tina Cascone, Annikka Weissferdt, Jianjun Zhang, Ara Vaporciyan, Boris Sepesi, Ferdinandos Skoulidis, Erin Corsini, Mara Antonoff, George Blumenschein, Yasir Elamin, Frank Fossella, Bonnie Glisson, Wayne Hofstetter, Jonathan Kurie, Xiuning Le, Cheuk Hong Leung, Reza Mehran, Frank Mott, David Rice, Jack Roth, Stephen Swisher, Anne Tsao, Garret Walsh, Don Gibbons
Published in Journal for ImmunoTherapy of Cancer (2020-11-01)Article -
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Poziotinib for EGFR exon 20-insertion NSCLC: Clinical efficacy of the phase 2 ZENITH trial and differential impact of EGFR exon 20 insertion location on sensitivity by Xiuning Le, Jacqulyne P. Robichaux, Monique Nilsson, R. S. K. Vijayan, Ashwin Ravichandran, Jia Wu, Yasir Y. Elamin, Lingzhi Hong, Jun Pei, Jun He, Sonia Patel, Hibiki Udagawa, Sriramvignesh Mani, Chang Woon Jang, Jeffrey M. Clarke, Nishan Tchekmedyian, Jonathan W. Goldman, Mark Socinski, Gajanan Bhat, Sharon Leu, Veronica Bunn, Zhenqiang Su, Sylvie Vincent, John W. Lawson, Jason B. Cross, John V. Heymach
Published in Nature Communications (2025-09-01)Get full text
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Nivolumab and ipilimumab with concurrent stereotactic radiosurgery for intracranial metastases from non-small cell lung cancer: analysis of the safety cohort for non-randomized, op... by Jing Li, Yan Wang, Chad Tang, James Welsh, Renata Ferrarotto, Mehmet Altan, Tina Cascone, Juhee Song, Marcelo V Negrao, John V Heymach, Brett W Carter, Ferdinandos Skoulidis, Yasir Y Elamin, Xiuning Le, Caroline Chung, George R Blumenschein, Nandita Guha-Thakurta, Jeffrey S Wefel, Amol J Ghia, Debra N Yeboa, Mary Frances McAleer, Kristina D Woodhouse, Susan L McGovern, Chenyang Wang, Betty Y S Kim, Jeffrey S Weinberg, Tina M Briere
Published in Journal for ImmunoTherapy of Cancer (2023-07-01)Get full text
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Machine-learning driven strategies for adapting immunotherapy in metastatic NSCLC by Maliazurina B. Saad, Qasem Al-Tashi, Lingzhi Hong, Vivek Verma, Wentao Li, Daniel Boiarsky, Shenduo Li, Milena Petranovic, Carol C. Wu, Brett W. Carter, Girish S. Shroff, Tina Cascone, Xiuning Le, Yasir Y. Elamin, Mehmet Altan, Simon Heeke, Ajay Sheshadri, Joe Y. Chang, Percy P. Lee, Zhongxing Liao, Don L. Gibbons, Ara A. Vaporciyan, J. Jack Lee, Ignacio I. Wistuba, Cara Haymaker, Seyedali Mirjalili, David Jaffray, Justin F. Gainor, Yanyan Lou, Alessandro Di Federico, Federica Pecci, Mark Awad, Biagio Ricciuti, John V. Heymach, Natalie I. Vokes, Jianjun Zhang, Jia Wu
Published in Nature Communications (2025-07-01)Get full text
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Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer by Lingzhi Hong, Muhammad Aminu, Shenduo Li, Xuetao Lu, Milena Petranovic, Maliazurina B. Saad, Pingjun Chen, Kang Qin, Susan Varghese, Waree Rinsurongkawong, Vadeerat Rinsurongkawong, Amy Spelman, Yasir Y. Elamin, Marcelo V. Negrao, Ferdinandos Skoulidis, Carl M. Gay, Tina Cascone, Saumil J. Gandhi, Steven H. Lin, Percy P. Lee, Brett W. Carter, Carol C. Wu, Mara B. Antonoff, Boris Sepesi, Jeff Lewis, Don L. Gibbons, Ara A. Vaporciyan, Xiuning Le, J. Jack Lee, Sinchita Roy-Chowdhuri, Mark J. Routbort, Justin F. Gainor, John V. Heymach, Yanyan Lou, Jia Wu, Jianjun Zhang, Natalie I. Vokes
Published in Nature Communications (2023-02-01)Get full text
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Enhancing NSCLC recurrence prediction with PET/CT habitat imaging, ctDNA, and integrative radiogenomics-blood insights by Sheeba J. Sujit, Muhammad Aminu, Tatiana V. Karpinets, Pingjun Chen, Maliazurina B. Saad, Morteza Salehjahromi, John D. Boom, Mohamed Qayati, James M. George, Haley Allen, Mara B. Antonoff, Lingzhi Hong, Xin Hu, Simon Heeke, Hai T. Tran, Xiuning Le, Yasir Y. Elamin, Mehmet Altan, Natalie I. Vokes, Ajay Sheshadri, Julie Lin, Jianhua Zhang, Yang Lu, Carmen Behrens, Myrna C. B. Godoy, Carol C. Wu, Joe Y. Chang, Caroline Chung, David A. Jaffray, Ignacio I. Wistuba, J. Jack Lee, Ara A. Vaporciyan, Don L. Gibbons, John Heymach, Jianjun Zhang, Tina Cascone, Jia Wu
Published in Nature Communications (2024-04-01)Get full text
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Analytical protocol to identify local ancestry-associated molecular features in cancer by Jian Carrot-Zhang, Seunghun Han, Wanding Zhou, Jeffrey S. Damrauer, Anab Kemal, Andrew D. Cherniack, Rameen Beroukhim, Ashton C. Berger, Matthew Meyerson, Katherine A. Hoadley, Ina Felau, Samantha Caesar-Johnson, John A. Demchok, Michael K.A. Mensah, Roy Tarnuzzer, Zhining Wang, Liming Yang, Jean C. Zenklusen, Nyasha Chambwe, Theo A. Knijnenburg, A. Gordon Robertson, Christina Yau, Christopher Benz, Kuan-lin Huang, Justin Newberg, Garret Frampton, R. Jay Mashl, Li Ding, Alessandro Romanel, Francesca Demichelis, Rosalyn W. Sayaman, Elad Ziv, Peter W. Laird, Hui Shen, Christopher K. Wong, Joshua M. Stuart, Alexander J. Lazar, Xiuning Le, Ninad Oak
Published in STAR Protocols (2021-12-01)Get full text
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Analysis of germline-driven ancestry-associated gene expression in cancers by Nyasha Chambwe, Rosalyn W. Sayaman, Donglei Hu, Scott Huntsman, Anab Kemal, Samantha Caesar-Johnson, Jean C. Zenklusen, Elad Ziv, Rameen Beroukhim, Andrew D. Cherniack, Jian Carrot-Zhang, Ashton C. Berger, Seunghun Han, Matthew Meyerson, Jeffrey S. Damrauer, Katherine A. Hoadley, Ina Felau, John A. Demchok, Michael K.A. Mensah, Roy Tarnuzzer, Zhining Wang, Liming Yang, Theo A. Knijnenburg, A. Gordon Robertson, Christina Yau, Christopher Benz, Kuan-lin Huang, Justin Y. Newberg, Garrett M. Frampton, R. Jay Mashl, Li Ding, Alessandro Romanel, Francesca Demichelis, Wanding Zhou, Peter W. Laird, Hui Shen, Christopher K. Wong, Joshua M. Stuart, Alexander J. Lazar, Xiuning Le, Ninad Oak
Published in STAR Protocols (2022-09-01)Get full text
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