Enteric Coating Enhances the Biopharmaceutical Performance of a Silica–Lipid Formulation of Abiraterone Acetate

<b>Background/Objectives:</b> Lipid-based formulations are widely used to enhance the oral bioavailability of poorly water-soluble drugs. However, for weakly basic drugs with higher solubility under acidic conditions, precipitation and recrystallisation after gastric emptying can comprom...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Ali Taheri, Ruba Almasri, Anthony Wignall, Felicia Feltrin, Kristen E. Bremmell, Paul Joyce, Clive A. Prestidge
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	mesoporous silica lipid-based formulation weakly basic drugs in vitro lipolysis in vivo pharmacokinetics enteric coating
Online Access:	https://www.mdpi.com/1999-4923/17/10/1289