UltraFast Layer-Resolved Encoding (uFLARE) functional MRI deciphers bidirectional signaling from spontaneous activity

Abstract Deciphering the directionality of information flow in cortical circuits is essential for understanding brain dynamics, learning, and neuroplasticity after injury. However, current noninvasive methods cannot distinguish bottom-up from top-down signals across entire networks, including deep b...

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Bibliographic Details
Published in:	Nature Communications
Main Authors:	Joana Carvalho, Francisca F. Fernandes, Mafalda Valente, Koen V. Haak, Noam Shemesh
Format:	Article
Language:	English
Published:	Nature Portfolio 2026-05-01
Online Access:	https://doi.org/10.1038/s41467-026-71506-9

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