Oxidative stress induces monocyte necrosis with enrichment of cell-bound albumin and overexpression of endoplasmic reticulum and mitochondrial chaperones.
In the present study, monocytes were treated with 5-azacytidine (azacytidine), gossypol or hydrogen peroxide to induce cell death through oxidative stress. A shift from apoptotic to necrotic cell death occurred when monocytes were treated with 100 µM azacytidine for more than 12 hours. Necrotic mono...
| 出版年: | PLoS ONE |
|---|---|
| 主要な著者: | Haiping Tang, Enbing Tian, Chongdong Liu, Qingtao Wang, Haiteng Deng |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
Public Library of Science (PLoS)
2013-01-01
|
| オンライン・アクセス: | http://europepmc.org/articles/PMC3608663?pdf=render |
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