Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives

Tyrosinase enzyme is a monophenol monoxygenase enzyme, which plays an important role in human as a rate limiting step enzyme for different specific metabolic pathways, as well as its useful application in industry and agriculture. So this study was carried out to test the effect of newly prepared co...

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Bibliographic Details
Published in:Molecules
Main Authors: Galila A. Yacout, Huda E. Abdelwahab, Seham Y. Hassan, Mohamed M. El Sadek
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Subjects:
carbohydrazide
oxadiazole
triazole
tyrosinase
Online Access:http://www.mdpi.com/1420-3049/18/7/8550
Description
Summary:Tyrosinase enzyme is a monophenol monoxygenase enzyme, which plays an important role in human as a rate limiting step enzyme for different specific metabolic pathways, as well as its useful application in industry and agriculture. So this study was carried out to test the effect of newly prepared compounds containing 1,3,4-oxadiazoles with different substituted groups on tyrosinase enzyme activity, hoping to use them in the treatment of some diseases arising from tyrosinase activity disorders such as Parkinson’s disease, schizophrenia, autism, attention deficit, hyperactivity disorder, and cancer.
ISSN:1420-3049

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