Insights into the Activities and Usefulness of Deoxynojirimycin and <i>Morus alba</i>: A Comprehensive Review

Deoxynojirimycin (DNJ), the first isolated iminosugar, is a natural alkaloid acting as a potent inhibitor of α-glucosidase with high nutritional value. It naturally occurs in plants (especially <i>Morus</i> spp.), microbes, and insects or can be synthesized. Diverse biological activities...

Full description

Bibliographic Details
Published in:	Molecules
Main Authors:	Angela Fulvia Tricase, Maria Maddalena Cavalluzzi, Alessia Catalano, Michela De Bellis, Annalisa De Palma, Giovanna Basile, Maria Stefania Sinicropi, Giovanni Lentini
Format:	Article
Language:	English
Published:	MDPI AG 2025-07-01
Subjects:	mulberry diabetes moranoline glycemic control
Online Access:	https://www.mdpi.com/1420-3049/30/15/3213

Similar Items

KADAR 1-DEOXYNOJIRIMYCIN DAN AKTIFITAS PENGHAMBATAN TERHADAP ENZIM Α-GLUKOSIDASE DALAM EKSTRAK, TEPUNG EKSTRAK DAN TEPUNG INSTANT DAUN MURBAI (Morus alba L) [1-Deoxynojirimycin Content and Inhibitory Activity on Α-Glucosidase Enzyme of Extract, Extract Powder and Instant Powder of Mulberry (Morus alba L)]
by: Kesuma Sayuti1)*, et al.
Published: (2010-12-01)

Transcriptome analysis and identification of key genes involved in 1-deoxynojirimycin biosynthesis of mulberry (Morus alba L.)
by: Dujun Wang, et al.
Published: (2018-08-01)

Morus alba: natural and valuable effects in weight loss management
by: Foteini Ntalouka, et al.
Published: (2024-10-01)

Response of Rhizosphere Microenvironment of Mulberry (<i>Morus alba</i> L.) to Different Cultivars
by: Chuanjie Chen, et al.
Published: (2025-09-01)

Effect of Frost on the Different Metabolites of Two Mulberry (<i>Morus nigra</i> L. and <i>Morus alba</i> L.) Leaves
by: Lu Yang, et al.
Published: (2023-06-01)

The Rheological Behavior of Polysaccharides from Mulberry Leaves (<i>Morus alba</i> L.)
by: Bu-Yan Liao, et al.
Published: (2020-08-01)

Antioxidant Activity and Mechanism of Resveratrol and Polydatin Isolated from Mulberry (<i>Morus alba</i> L.)
by: Ziwei Li, et al.
Published: (2021-12-01)

Metabolomics Response to Drought Stress in <i>Morus alba</i> L. Variety Yu-711
by: Michael Ackah, et al.
Published: (2021-08-01)

Determination of 1-Deoxynojirimycin (1-DNJ) in Leaves of Italian or Italy-Adapted Cultivars of Mulberry (<i>Morus</i> sp.pl.) by HPLC-MS
by: Lucia Marchetti, et al.
Published: (2021-07-01)

An In-Depth Examination of Phytochemicals and Medicinal Uses on <i>Morus alba</i>
by: Roshan Kumar Dubey, et al.
Published: (2024-12-01)

Phytochemical and antimicrobial properties of Morus nigra and Morus alba grown in Fujairah, United Arab Emirates
by: Aishah Al Dhanhani, et al.
Published: (2025-10-01)

Transcriptome Analysis of <i>Morus alba</i> L. Flower Reveals Important Genes of Floral Sex Differentiation
by: Dashun Xu, et al.
Published: (2022-07-01)

Evaluation of Antioxidant and Antibacterial Activities of White Mulberry (<i>Morus alba</i> L.) Fruit Extracts
by: Sureeporn Suriyaprom, et al.
Published: (2021-12-01)

Characterization of cellulosic fibers from Morus alba L. stem
by: R. Prithivirajan, et al.
Published: (2019-05-01)

Effects of Mulberry Fruit (Morus alba L.) Consumption on Health Outcomes: A Mini-Review
by: Hongxia Zhang, et al.
Published: (2018-05-01)

Quantitative determination of 1-deoxynojirimycin in 146 varieties of mulberry fruit
by: Zhenjiang Wang, et al.
Published: (2021-01-01)

Elicitation of Stilbenes and Benzofuran Derivatives in Hairy Root Cultures of White Mulberry (<i>Morus alba</i>)
by: Lingling Fang, et al.
Published: (2022-12-01)

How Does <i>In Vitro</i> Digestion Change the Amount of Phenolics in <i>Morus alba</i> L. Leaf? Analysis of Preparations and Infusions
by: Monika Przeor
Published: (2024-01-01)

Quality Assessment of Dried White Mulberry (<i>Morus alba L.)</i> Using Machine Vision
by: Adel Hosainpour, et al.
Published: (2022-11-01)

Characterization of Genetic Diversity of Mulberry (<i>Morus alba</i>) Genotypes Growing Naturally in Northeastern Türkiye (Kelkit Valley) Using Morphological, Biochemical, and Molecular Markers
by: Ahmet Sümbül
Published: (2025-03-01)

The Volumetrical, Geometrical and Frictional Properties of White Mulberry (Morus alba L.) Fruits
by: Ebubekir Altuntaş
Published: (2016-11-01)

Current anti-diabetes mechanisms and clinical trials using Morus alba L.
by: Simin Tian, et al.
Published: (2016-01-01)

Effects of Dietary Mulberry Leaves (Morus alba L.) on Egg Yolk Color
by: Kanda Lokaewmanee, et al.
Published: (2009-04-01)

Evaluation of the Chemical Composition and Antioxidant Activity of Mulberry (<i>Morus alba</i> L.) Fruits from Different Varieties in China
by: Tao Chen, et al.
Published: (2022-04-01)

Genome-Wide Identification of Candidate Genes Associated with Heat Stress in Mulberry (<i>Morus alba</i> L.)
by: Xin Jin, et al.
Published: (2023-05-01)

LC-MS Metabolite Profiling and the Hypoglycemic Activity of <i>Morus alba</i> L. Extracts
by: Qing Yi-Jun Zhou, et al.
Published: (2022-08-01)

Toxicity potential in the extraneous compounds of white mulberry wood (morus alba)
by: Aida Se Golpayegani, et al.
Published: (2014-12-01)

La morera (Morus alba, Linn.): una especie de interés para la alimentación animal Mulberry (Morus alba, Linn.): a species of interest for livestock production
by: G.J Martín, et al.
Published: (2007-12-01)

Comparison of fatty acid profile and mineral content of black mulberry (Morus nigra), white mulberry (Morus alba) and red mulberry (Morus rubra) grown in Bahrain
by: Ali Ali Redha, et al.
Published: (2023-12-01)

Identification and Characterization of a Novel Quanzhou Mulberry Virus from Mulberry (<i>Morus alba</i>)
by: Jia Wei, et al.
Published: (2023-05-01)

Bioactive Compounds Produced in Leaves of Mulberry (<i>Morus alba</i> L.) Transplants under Modified Environments of Root and Aerial Zones
by: Aye Nwe Win, et al.
Published: (2022-10-01)

Antioxidant and Anti-Inflammatory Activity on LPS-Stimulated RAW 264.7 Macrophage Cells of White Mulberry (<i>Morus alba</i> L.) Leaf Extracts
by: Sureeporn Suriyaprom, et al.
Published: (2023-05-01)

The Effect of Drying Variables on the Microwave–Vacuum-Drying Characteristics of Mulberries (<i>Morus alba</i> L.): Experiments and Multivariate Models
by: Yuyang Cong, et al.
Published: (2023-09-01)

Effects of Growth Period and Storage Methods on Primary Metabolite Contents and Antioxidant Activities of <i>Morus alba</i> L. Leaf
by: Lei Hu, et al.
Published: (2022-12-01)

Molecular and metabolic insights into purplish leaf coloration through the investigation of two mulberry (Morus alba) genotypes
by: Shusong Li, et al.
Published: (2024-01-01)

Chemical composition and ruminal digestion of corn silage with Morus alba L. foliage
by: Regulo Jimenéz-Guillén, et al.
Published: (2019-12-01)

Impact of Tea Processing on Tryptophan, Melatonin, Phenolic and Flavonoid Contents in Mulberry (<i>Morus alba</i> L.) Leaves: Quantitative Analysis by LC-MS/MS
by: Panyada Panyatip, et al.
Published: (2022-08-01)

Mulberry (<i>Morus alba</i>) Twig and Leaf Extracts Ameliorate Obesity-Related Metabolic Disorders via Gut Microbiota Modulation in High-Fat Diet-Fed Mice
by: Wei Qian, et al.
Published: (2025-06-01)

Varietal Performance of Sweet Potato (Ipomoea batatas l.) Planted in Between Mulberry (Morus alba l.) Trees
by: Mark Anthony A. Boisa, et al.
Published: (2025-09-01)

UV-B Induced Changes in the Secondary Metabolites of Morus alba L. Leaves
by: Da-Wei Zhang, et al.
Published: (2010-04-01)