ProNGF and Neurodegeneration in Alzheimer’s Disease

Profound and early basal forebrain cholinergic neuron (BFCN) degeneration is a hallmark of Alzheimer’s disease (AD). Loss of synapses between basal forebrain and hippocampal and cortical target tissue correlates highly with the degree of dementia and is thought to be a major contributor to memory lo...

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Bibliographic Details
Published in:	Frontiers in Neuroscience
Main Authors:	Margaret Fahnestock, Arman Shekari
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-02-01
Subjects:	nerve growth factor TrkA p75NTR neurotrophins basal forebrain cholinergic neurons survival
Online Access:	https://www.frontiersin.org/article/10.3389/fnins.2019.00129/full

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