The Contact Allergen NiSO4 Triggers a Distinct Molecular Response in Primary Human Dendritic Cells Compared to Bacterial LPS

Dendritic cells (DC) play a central role in the pathogenesis of allergic contact dermatitis (ACD), the most prevalent form of immunotoxicity in humans. However, knowledge on allergy-induced DC maturation is still limited and proteomic studies, allowing to unravel molecular effects of allergens, rema...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Tessa Höper, Katherina Siewert, Verónica I. Dumit, Martin von Bergen, Kristin Schubert, Andrea Haase
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-03-01
Subjects:	monocyte-derived dendritic cells allergic contact dermatitis proteomics nickel LPS
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.644700/full