Association of Endothelial Cell Activation with Acute Kidney Injury during Coronary Angiography and the Influence of Recombinant Human C1 Inhibitor—A Secondary Analysis of a Randomized, Placebo-Controlled, Double-Blind Trial

Background: Acute kidney injury (AKI) as a result of iodinated contrast media (CM) has been linked to CM-induced renal ischemia and toxic effects on endothelial cells (EC). The recombinant human C1 inhibitor (rhC1INH) has been shown to influence EC activation. Methods: Secondary analysis of 74/77 (9...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Stephan Moser, Laura Araschmid, Anneza Panagiotou, Leo H. Bonati, Tobias Breidthardt, Gregor Fahrni, Christoph Kaiser, Raban Jeger, Marten Trendelenburg, Michael Osthoff
Format: Article
Language:English
Published: MDPI AG 2024-08-01
Subjects:
endothelial cell activation
complement system
C1 inhibitor
contrast media
ICAM-1
VCAM-1
Online Access:https://www.mdpi.com/2227-9059/12/9/1956

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https://www.mdpi.com/2227-9059/12/9/1956

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