Association of Endothelial Cell Activation with Acute Kidney Injury during Coronary Angiography and the Influence of Recombinant Human C1 Inhibitor—A Secondary Analysis of a Randomized, Placebo-Controlled, Double-Blind Trial

Background: Acute kidney injury (AKI) as a result of iodinated contrast media (CM) has been linked to CM-induced renal ischemia and toxic effects on endothelial cells (EC). The recombinant human C1 inhibitor (rhC1INH) has been shown to influence EC activation. Methods: Secondary analysis of 74/77 (9...

Full description

Bibliographic Details
Published in:	Biomedicines
Main Authors:	Stephan Moser, Laura Araschmid, Anneza Panagiotou, Leo H. Bonati, Tobias Breidthardt, Gregor Fahrni, Christoph Kaiser, Raban Jeger, Marten Trendelenburg, Michael Osthoff
Format:	Article
Language:	English
Published:	MDPI AG 2024-08-01
Subjects:	endothelial cell activation complement system C1 inhibitor contrast media ICAM-1 VCAM-1
Online Access:	https://www.mdpi.com/2227-9059/12/9/1956

Similar Items

Complement and endothelial cell activation in COVID-19 patients compared to controls with suspected SARS-CoV-2 infection: A prospective cohort study
by: Flavio Bruni, et al.
Published: (2022-09-01)

Study of Adhesion Molecules in Diabetes Mellitus Type2 Iraqi Patients with Dyslipidemia
by: Abbas M. Alsaedy, et al.
Published: (2024-07-01)

Serum level of endothelial markers in patients with psoriasis vulgaris with or without arteriogenic erectile dysfunction
by: Elsayed Zayed, et al.
Published: (2022-01-01)

The Lectin Pathway of Complement in Myocardial Ischemia/Reperfusion Injury—Review of Its Significance and the Potential Impact of Therapeutic Interference by C1 Esterase Inhibitor
by: Anneza Panagiotou, et al.
Published: (2018-05-01)

Immunohistochemical Analysis of Adhesion Molecules E-Selectin, Intercellular Adhesion Molecule-1, and Vascular Cell Adhesion Molecule-1 in Inflammatory Lesions of Atopic Dermatitis
by: Sandra Marinović Kulišić, et al.
Published: (2023-04-01)

Ginsenoside Rb1 alleviates oxidative damage of HUVECs
by: SONG Zhi-ming, YU Shu-jie, JIAO Jie, LI Ping-ping, LI Hong-mei, QIAN Xiao-xian
Published: (2020-08-01)

Endothelial molecule levels (VCAM-1, ICAM-1) in uncomplicated malaria cases in Lagos, Nigeria
by: Uche T. Igbasi, et al.
Published: (2024-12-01)

ICAM1 and VCAM1 are associated with outcome in patients with sepsis: A systematic review and meta-analysis
by: Jiawei He, et al.
Published: (2024-11-01)

The Effects of Endurance Training with Genistein on ICAM-1, VCAM-1, and CRP of Diabetic Rats
by: Sirous Farsi, et al.
Published: (2016-09-01)

Changes of Serum Intercellular Adhesion Molecule – 1, Vascular Adhesion Molecule-1 and C – Reactive Protein in Middle-Aged Men with Heart Failure after Eight Weeks of Aerobic Exercise
by: Hoda Haghir, et al.
Published: (2017-03-01)

The Effect of an Annona muricata Leaves Extract on Circulating Soluble Adhesion Molecules in Colon Carcinogenesis Model
by: Lili Indrawati, et al.
Published: (2023-04-01)

CSF Levels of Baseline VCAM-1 and ICAM-1 Are Associated with Tau Pathology in Patients Demonstrating Cognitive Impairment
by: Manal Aljuhani, et al.
Published: (2026-04-01)

Evaluation of biochemical and clinical markers of endothelial dysfunction and their correlation with urinary albumin excretion in patients with type 1 diabetes mellitus
by: Sefika Burcak Polat, et al.
Published: (2016-02-01)

Endothelial function/damage markers and NGAL – intraoperative assessment in blood specimens obtained from different sampling sites during open repair of abdominal aortic aneurysm
by: Michał Kokot, et al.
Published: (2025-02-01)

Upregulation of sICAM-1 and sVCAM-1 Levels in the Cerebrospinal Fluid of Patients with Schizophrenia Spectrum Disorders
by: Sophie Meixensberger, et al.
Published: (2021-06-01)

The Effects of Resistance Training on VCAM-1, ICAM-1 and CRP in Diabetic Rats
by: Somaye Pouranfar, et al.
Published: (2019-03-01)

Disturbance in the composition of lipoprotein particles and chronic inflammation as prognostic factors in the development of coronary disease
by: Jovović Biljana, et al.
Published: (2007-01-01)

Angiotensin-(1-7) Attenuates Angiotensin II-Induced ICAM-1, VCAM-1, and MCP-1 Expression via the MAS Receptor Through Suppression of P38 and NF-κB Pathways in HUVECs
by: Bin Liang, et al.
Published: (2015-04-01)

A Survey of interval training on the expression of ICAM, VCAM and galectin-3 proteins in the heart tissue of asthmatic rats
by: Masome Nobahar, et al.
Published: (2021-10-01)

Pathomorphological diagnostics of chronic appendicitis (literature review)
by: N. N. Dremina, et al.
Published: (2017-09-01)

Panduratin A Inhibits TNF Alpha-Stimulated Endothelial Cell Activation Through Suppressing the NF-κB Pathway
by: Kriangkrai Kiatsoonthon, et al.
Published: (2024-12-01)

The Vascular Circadian Clock in Chronic Kidney Disease
by: Søren Egstrand, et al.
Published: (2021-07-01)

Effect of 8-week Swimming training and garlic intake on serum ICAM and VCAM adhesion molecules in male obese rats.
by: Shahin Riyahi Malayeri, et al.
Published: (2019-01-01)

An Assessment of Endothelial Markers in Patients with Uncomplicated Malaria in Jazan Province, Saudi Arabia
by: Madkhali A, et al.
Published: (2025-06-01)

人工寒潮促发大鼠脑卒中发病前脑血管内皮细胞粘附分子的变化
Published: (2009-01-01)

Protective Effects of Extracts from Green Leaves and Rhizomes of <i>Posidonia oceanica</i> (L.) Delile on an In Vitro Model of the Human Blood–Brain Barrier
by: Giulia Abruscato, et al.
Published: (2025-06-01)

Effect of six weeks forced and voluntary training before EAE induction on the expression of some adhesive molecules affecting the blood-brain barrier permeability
by: Mohammad Reza Rahmati, et al.
Published: (2022-03-01)

Serum Soluble Adhesion Molecules (sICAM-1, sVCAM-1 and sE-Selectin) in Healthy School Aged Children and Adults
by: Ctirad Andrýs, et al.
Published: (2000-01-01)

Serum Soluble Adhesion Molecules (sICAM-1, sVCAM-1, sE-selectin) and Neopterin in Patients with Sjögren's Syndrome
by: Ctirad Andrýs, et al.
Published: (1999-01-01)

Serum ICAM-1 and VCAM-1 as markers of endothelial activation in ankylosing spondylitis and psoriatic arthritis: a cross-sectional study
by: Miroslav Markov, et al.
Published: (2026-04-01)

Increased endothelial biomarkers are associated with HIV antiretroviral therapy and C-reactive protein among a African rural population in Limpopo Province, South Africa
by: Sidney Hanser, et al.
Published: (2022-11-01)

Influence of short-term changes in sex hormones on serum concentrations of cellular adhesion molecules in young healthy women
by: Ivana Begić, et al.
Published: (2012-02-01)

Diagnostic and prognostic significance of some inflammatory serum proteins in patients with precancerous diseases and cervical cancer
by: E. V. Kayukova, et al.
Published: (2021-08-01)

Activation of integrin signaling up-regulates pro-inflammatory cytokines in JAK2-V617F positive hematopoietic cells
by: Conny K. Baldauf, et al.
Published: (2025-08-01)

The Content of Intercellular Adhesion Molecules in Patients With COVID-19-Associated Lung Disease
by: A. M. Karachenova, et al.
Published: (2025-05-01)

The Effect of Eight-Week Aerobic Exercises on Vascular Cellular Adhesion Molecule-1, Intracellular Adhesion Molecule and Body Composition of Addicts Treated with Methadone
by: Mahboobeh Zibandepoor, et al.
Published: (2019-09-01)

Dual implication of endothelial adhesion molecules in tumor progression and cancer immunity
by: Louis-Emmanuel Chriqui, et al.
Published: (2025-12-01)

Levels of VCAM-1 and ICAM-1 in serum of active and inactive Systemic Lupus Erythematosus patients as biochemical markers for risk of cardiovascular disease
by: Hajer Walid, et al.
Published: (2024-01-01)

Increased Levels of VCAM-1 in Patients with High Cardiovascular Risk and Obstructive Sleep Apnea Syndrome
by: Ioana-Maria Chetan, et al.
Published: (2023-12-01)

Puerarin attenuates the inflammatory response of vascular endothelial cells in KKAy mice
by: ZOU Jie, ZHANG Dede, TAO Yi, ZHAO Jing, WANG Qiong, XU Naijia
Published: (2023-03-01)