The Assessment of Calcium and Bleomycin Cytotoxic Efficiency in Relation to Cavitation Dosimetry
Microbubble (MB)- and ultrasound (US)-facilitated intracellular Ca<sup>2+</sup> delivery, known as sonoporation (SP), is a promising anticancer treatment modality, since it allows a spatio-temporally controllable and side-effect-free alternative to conventional chemotherapy. The current...
| Published in: | Pharmaceutics |
|---|---|
| Main Authors: | Martynas Maciulevičius, Renaldas Raišutis, Baltramiejus Jakštys, Linas Svilainis, Andrius Chaziachmetovas, Saulius Šatkauskas |
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-05-01
|
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4923/15/5/1463 |
Similar Items
Sudden Cell Death Induced by Ca<sup>2+</sup> Delivery via Microbubble Cavitation
by: Martynas Maciulevičius, et al.
Published: (2021-01-01)
by: Martynas Maciulevičius, et al.
Published: (2021-01-01)
Ca2+ sonotransfer into breast cancer cells in a suspension, 3-D spheroid and subcutaneous tumor models
by: Martynas Maciulevičius, et al.
Published: (2025-07-01)
by: Martynas Maciulevičius, et al.
Published: (2025-07-01)
Influence of cell shape on sonoporation efficiency in microbubble-facilitated delivery using micropatterned cell arrays
by: Mirza Albash Baig, et al.
Published: (2024-12-01)
by: Mirza Albash Baig, et al.
Published: (2024-12-01)
Investigation of an Optical Imaging Platform Integrated with an Ultrasound Application System for In Vitro Verification of Ultrasound-Mediated Drug Delivery
by: Jong-ryul Choi, et al.
Published: (2021-03-01)
by: Jong-ryul Choi, et al.
Published: (2021-03-01)
Microbubble–Nanoparticle Complexes for Ultrasound-Enhanced Cargo Delivery
by: Rachel Chapla, et al.
Published: (2022-11-01)
by: Rachel Chapla, et al.
Published: (2022-11-01)
Stable Cavitation-Mediated Delivery of miR-126 to Endothelial Cells
by: Stephanie He, et al.
Published: (2022-11-01)
by: Stephanie He, et al.
Published: (2022-11-01)
Analysis of Microbubble-Blood cell system Oscillation/Cavitation influenced by ultrasound Forces: Conjugate applications of FEM and LBM
by: Ramyar Doustikhah, et al.
Published: (2024-08-01)
by: Ramyar Doustikhah, et al.
Published: (2024-08-01)
Sonoporation: Underlying Mechanisms and Applications in Cellular Regulation
by: Yue Li, et al.
Published: (2021-04-01)
by: Yue Li, et al.
Published: (2021-04-01)
Ultrasound and Microbubbles Enhance Uptake of Doxorubicin in Murine Kidneys
by: Oystein Eikrem, et al.
Published: (2021-11-01)
by: Oystein Eikrem, et al.
Published: (2021-11-01)
Efficacy and Safety of Low-Intensity Pulsed Ultrasound-Induced Blood–Retinal Barrier Opening in Mice
by: Alexandre Bourdin, et al.
Published: (2023-07-01)
by: Alexandre Bourdin, et al.
Published: (2023-07-01)
Sonoporation with Echogenic Liposomes: The Evaluation of Glioblastoma Applicability Using In Vivo Xenograft Models
by: Ju-Hyun Park, et al.
Published: (2025-04-01)
by: Ju-Hyun Park, et al.
Published: (2025-04-01)
Cationic Microbubbles for Non-Selective Binding of Cavitation Nuclei to Bacterial Biofilms
by: Gareth LuTheryn, et al.
Published: (2023-05-01)
by: Gareth LuTheryn, et al.
Published: (2023-05-01)
Harnessing Ultrasonic Technologies to Treat <i>Staphylococcus Aureus</i> Skin Infections
by: John Hulme
Published: (2025-01-01)
by: John Hulme
Published: (2025-01-01)
Sonoporation Using Nanoparticle-Loaded Microbubbles Increases Cellular Uptake of Nanoparticles Compared to Co-Incubation of Nanoparticles and Microbubbles
by: Sofie Snipstad, et al.
Published: (2021-04-01)
by: Sofie Snipstad, et al.
Published: (2021-04-01)
Enhanced Amikacin Diffusion With Ultrasound and Microbubbles in a Mechanically Ventilated Condensed Lung Rabbit Model
by: Fabien Espitalier, et al.
Published: (2020-01-01)
by: Fabien Espitalier, et al.
Published: (2020-01-01)
Formulation and characterisation of drug-loaded antibubbles for image-guided and ultrasound-triggered drug delivery
by: Spiros Kotopoulis, et al.
Published: (2022-04-01)
by: Spiros Kotopoulis, et al.
Published: (2022-04-01)
The Influence of Calcium Ions on the Electrotransfer Efficiency of Plasmid DNA and Cell Viability
by: Rūta Palepšienė, et al.
Published: (2023-02-01)
by: Rūta Palepšienė, et al.
Published: (2023-02-01)
Sonoporation of Cells by a Parallel Stable Cavitation Microbubble Array
by: Long Meng, et al.
Published: (2019-09-01)
by: Long Meng, et al.
Published: (2019-09-01)
Effect of ultrasound-microbubble exposure on acute myeloid leukemia cancer cell proteome
by: Joelle Stilwell, et al.
Published: (2025-08-01)
by: Joelle Stilwell, et al.
Published: (2025-08-01)
Development of exosome membrane materials-fused microbubbles for enhanced stability and efficient drug delivery of ultrasound contrast agent
by: Yongho Jang, et al.
Published: (2023-12-01)
by: Yongho Jang, et al.
Published: (2023-12-01)
Sonochemotherapy: From bench to bedside
by: Bart eLammertink, et al.
Published: (2015-07-01)
by: Bart eLammertink, et al.
Published: (2015-07-01)
Electrochemical generation of microbubbles by carbon nanotube interdigital electrodes to increase the permeability and material uptakes of cancer cells
by: Mohammad Ali Khayamian, et al.
Published: (2019-01-01)
by: Mohammad Ali Khayamian, et al.
Published: (2019-01-01)
Overcoming anticancer resistance by photodynamic therapy-related efflux pump deactivation and ultrasound-mediated improved drug delivery efficiency
by: Doyeon Kim, et al.
Published: (2020-09-01)
by: Doyeon Kim, et al.
Published: (2020-09-01)
Regulating microbubble clusters for improving temporal uniformity of stable cavitation intensity under rapid short-pulse ultrasound
by: Qizheng Zhou, et al.
Published: (2025-11-01)
by: Qizheng Zhou, et al.
Published: (2025-11-01)
Pingyangmycin and Bleomycin Share the Same Cytotoxicity Pathway
by: Yanli He, et al.
Published: (2016-06-01)
by: Yanli He, et al.
Published: (2016-06-01)
Enhanced cavitation dose and reactive oxygen species production in microbubble-mediated sonodynamic therapy for inhibition of Escherichia coli and biofilm
by: Changlong Li, et al.
Published: (2024-05-01)
by: Changlong Li, et al.
Published: (2024-05-01)
Applications of Ultrasound-Mediated Gene Delivery in Regenerative Medicine
by: Zoe Krut, et al.
Published: (2022-04-01)
by: Zoe Krut, et al.
Published: (2022-04-01)
Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells
by: Ragnhild Haugse, et al.
Published: (2020-11-01)
by: Ragnhild Haugse, et al.
Published: (2020-11-01)
The molecular impact of sonoporation: A transcriptomic analysis of gene regulation profile
by: Xinxing Duan, et al.
Published: (2024-12-01)
by: Xinxing Duan, et al.
Published: (2024-12-01)
Synergistic enhancement of cell death by triple combination therapy of docetaxel, ultrasound and microbubbles, and radiotherapy on PC3 a prostate cancer cell line
by: Firas Almasri, et al.
Published: (2022-08-01)
by: Firas Almasri, et al.
Published: (2022-08-01)
Ultrasound and microbubble induced release from intracellular compartments
by: Farah Hussein, et al.
Published: (2017-05-01)
by: Farah Hussein, et al.
Published: (2017-05-01)
The Evidence of the Bystander Effect after Bleomycin Electrotransfer and Irreversible Electroporation
by: Paulius Ruzgys, et al.
Published: (2021-10-01)
by: Paulius Ruzgys, et al.
Published: (2021-10-01)
Cavitation Characterization of Size-Isolated Microbubbles in a Vessel Phantom Using Focused Ultrasound
by: Payton Martinez, et al.
Published: (2022-09-01)
by: Payton Martinez, et al.
Published: (2022-09-01)
Enhancement of High-Intensity Focused Ultrasound Heating by Short-Pulse Generated Cavitation
by: Shin Yoshizawa, et al.
Published: (2017-03-01)
by: Shin Yoshizawa, et al.
Published: (2017-03-01)
Detection of ultrasonic cavitation based on low-frequency analysis of acoustic signal
by: Brabec Kamil, et al.
Published: (2007-06-01)
by: Brabec Kamil, et al.
Published: (2007-06-01)
Microfluidic Monodispersed Microbubble Generation for Production of Cavitation Nuclei
by: Renjie Ning, et al.
Published: (2024-12-01)
by: Renjie Ning, et al.
Published: (2024-12-01)
Pulmonary cytotoxicity induced by bleomycin and methotrexate
by: Zh, V, Sheykh, et al.
Published: (2016-03-01)
by: Zh, V, Sheykh, et al.
Published: (2016-03-01)
Evaluation of the properties of daughter bubbles generated by inertial cavitation of preformed microbubbles
by: Yanglin Li, et al.
Published: (2021-04-01)
by: Yanglin Li, et al.
Published: (2021-04-01)
Ultrasound-Mediated Membrane Modulation for Biomedical Applications
by: Jinhee Yoo, et al.
Published: (2025-06-01)
by: Jinhee Yoo, et al.
Published: (2025-06-01)
Non-Cavitation Targeted Microbubble-Mediated Single-Cell Sonoporation
by: Xiufang Liu, et al.
Published: (2022-01-01)
by: Xiufang Liu, et al.
Published: (2022-01-01)
Similar Items
-
Sudden Cell Death Induced by Ca<sup>2+</sup> Delivery via Microbubble Cavitation
by: Martynas Maciulevičius, et al.
Published: (2021-01-01) -
Ca2+ sonotransfer into breast cancer cells in a suspension, 3-D spheroid and subcutaneous tumor models
by: Martynas Maciulevičius, et al.
Published: (2025-07-01) -
Influence of cell shape on sonoporation efficiency in microbubble-facilitated delivery using micropatterned cell arrays
by: Mirza Albash Baig, et al.
Published: (2024-12-01) -
Investigation of an Optical Imaging Platform Integrated with an Ultrasound Application System for In Vitro Verification of Ultrasound-Mediated Drug Delivery
by: Jong-ryul Choi, et al.
Published: (2021-03-01) -
Microbubble–Nanoparticle Complexes for Ultrasound-Enhanced Cargo Delivery
by: Rachel Chapla, et al.
Published: (2022-11-01)
