Global distribution and impact of knockdown resistance mutations in Aedes aegypti on pyrethroid resistance

Abstract The ongoing fight against mosquito-borne diseases such as dengue, Zika, and chikungunya is increasingly challenged by Aedes aegypti resistance to pyrethroid insecticides. This resistance is primarily driven by knockdown resistance (kdr) mutations in the voltage-gated sodium channel (Vgsc) g...

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Bibliographic Details

Published in:	Parasites & Vectors
Main Authors:	Javier Tognarelli, Pablo R. Moya, Christian R. González, Ximena Collao-Ferrada
Format:	Article
Language:	English
Published:	BMC 2025-09-01
Subjects:	Aedes aegypti Pyrethroids Insecticide resistance Knockdown resistance kdr Sodium channel
Online Access:	https://doi.org/10.1186/s13071-025-06817-9