Non-Cationic RGD-Containing Protein Nanocarrier for Tumor-Targeted siRNA Delivery

Despite the recent successes in siRNA therapeutics, targeted delivery beyond the liver remains the major hurdle for the widespread application of siRNA in vivo. Current cationic liposome or polymer-based delivery agents are restricted to the liver and suffer from off-target effects, poor clearance,...

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Bibliographic Details
Published in:	Pharmaceutics
Main Authors:	Xiaolin Yu, Lu Xue, Jing Zhao, Shuhua Zhao, Daqing Wu, Hong Yan Liu
Format:	Article
Language:	English
Published:	MDPI AG 2021-12-01
Subjects:	RGD siRNA delivery tumor targeting tumor neo-vasculature integrin α<sub>v</sub>β<sub>3</sub> dsRNA binding domain
Online Access:	https://www.mdpi.com/1999-4923/13/12/2182

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