Antibacterial and Wound-Healing Activities of Statistically Optimized Nitrofurazone- and Lidocaine-Loaded Silica Microspheres by the Box–Behnken Design

In the current study, nitrofurazone- (NFZ) and lidocaine-loaded (LD) silica microspheres were fabricated to address pathological indications of skin infections. The microspheres were prepared by the sol–gel method applying the Box–Behnken design and evaluated for size distribution, morphology, zeta...

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Bibliographic Details
Published in:Molecules
Main Authors: Hafeez Ullah Khan, Fahmeed Nasir, Safirah Maheen, Syed Salman Shafqat, Shahid Shah, Ahmed Khames, Mohammed M. Ghoneim, Ghulam Abbas, Saleha Shabbir, Mohamed A. Abdelgawad, Mohammad A. S. Abourehab, Amna Irfan, Amani M. El Sisi
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Subjects:
antibacterial therapeutics
Box–Behnken design
lidocaine
nitrofurazone
silica microspheres
Online Access:https://www.mdpi.com/1420-3049/27/8/2532

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