Sodium butyrate attenuates microglia-mediated neuroinflammation by modulating the TLR4/MyD88/NF-κB pathway and microbiome-gut-brain axis in cardiac arrest mice

Abstract Cardiac arrest (CA) is one of the most common illnesses worldwide. Post-CA brain injury (PCABI) is a major cause of death and poor recovery in CA patients and the current CA treatments are not very effective. The microbiome-gut-brain axis has been found to significantly affect brain ischemi...

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Bibliographic Details
Published in:	Molecular Brain
Main Authors:	Jianfei Sun, Liping Lu, Yingtao Lian, Song Xu, Ying Zhu, Yanping Wu, Qianhui Lin, Jing Hou, Yinping Li, Zhui Yu
Format:	Article
Language:	English
Published:	BMC 2025-02-01
Subjects:	Cardiac arrest Microglia Sodium butyrate TLR4/MyD88/NF-κB pathway Neuroinflammation Gut microbiota
Online Access:	https://doi.org/10.1186/s13041-025-01179-w

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