Heyde’s syndrome as a rare cause of gastrointestinal bleeding in aortic stenosis patients

Heyde’s syndrome is one of the causes of gastrointestinal bleeding in patients with heart disease. It is characterized by the acquired destruction of high molecular weight multimers of von Willebrand factor due to high hydraulic shear stress on the aortic valve in severe stenosis, followed by gastro...

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Bibliographic Details
Published in:Кардиоваскулярная терапия и профилактика
Main Authors: D. V. Belov, D. V. Garbuzenko, O. P. Lukin, S. S. Anufrieva
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2021-02-01
Subjects:
heyde’s syndrome
aortic stenosis
gastrointestinal bleeding
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2503
Description
Summary:Heyde’s syndrome is one of the causes of gastrointestinal bleeding in patients with heart disease. It is characterized by the acquired destruction of high molecular weight multimers of von Willebrand factor due to high hydraulic shear stress on the aortic valve in severe stenosis, followed by gastrointestinal bleeding due to angiodysplasias. Management of such patients is a complex and relevant problem. The central method of treatment for Heyde’s syndrome is aortic valve replacement, which reduces the risk of recurrent gastrointestinal bleeding in more than 90% of patients.
ISSN:1728-8800
2619-0125

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