Research progress on botulinum toxin type A in the treatment of Raynaud's phenomenon

Raynaud's phenomenon is a common vasospasm response, and current medical therapies and surgical treatments show limited clinical effects. Botulinum toxin type A has certain effectiveness and safety in treating Raynaud's phenomenon. It can relax blood vessels, relieve pain, and has a good l...

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Bibliographic Details
Published in:Jichu yixue yu linchuang
Main Author: WANG Yuan-zhuo, ZHENG Qing-yue, ZHANG Han-lin, TANG Ke-yun, FANG Rou-yu, SUN Qiu-ning
Format: Article
Language:Chinese
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-10-01
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Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-10-1611.pdf
Description
Summary:Raynaud's phenomenon is a common vasospasm response, and current medical therapies and surgical treatments show limited clinical effects. Botulinum toxin type A has certain effectiveness and safety in treating Raynaud's phenomenon. It can relax blood vessels, relieve pain, and has a good long-term effect. Its side effects are mild, such as pain at the injection site, bruises, or transient muscle weakness. In recent years, some research has broadened the scope of application of the treatment and determined more effective injection doses and injection methods to reduce the side effects. More large-sample randomized double-blind controlled trials and animal experiments are needed to provide information for explaining the treatment mechanisms and illstrating the efficacy.
ISSN:1001-6325