Exogenous Galectin-9 prevents peri-implantitis in rats by regulating macrophage polarization

BackgroundPeri-implantitis (PI) is a common complication of oral implants with no definitive treatment strategy. Lipopolysaccharides (LPS) are involved in PI by activating macrophages and influencing osteoclasts and osteoblasts. Galactin-9 (Gal-9) is known for its immunomodulatory properties and int...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Lujin Cheng, Xiaowei Ji, Huerxidai Yilihamujiang, Shuya Dong, Long Mei, Guo Lin, Qihan Tang, Zhongcheng Gong
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Subjects:	peri-implantitis rat Galectin-9 macrophage polarization alveolar bone resorption
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2025.1533468/full