Chimeric RNA Design Principles for RNA-Mediated Gene Fusion

One common genetic alteration in cancer is gene fusion resulting from chromosomal translocations. The mechanisms that create such oncogenic fusion genes are not well understood. Previously, we provided the direct evidence that expression of a designed chimeric RNA can drive the formation of TMPRSS2-...

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Bibliographic Details
Published in:	Cells
Main Authors:	Sachin Kumar Gupta, Laising Yen
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Subjects:	TMPRSS2-ERG chimeric RNA gene fusion genomic recombination prostate cancer
Online Access:	https://www.mdpi.com/2073-4409/11/6/1002

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