| الملخص: | Plantaricin Q7 is a broad-spectrum antimicrobial peptide produced by <i>Lactobacillus plantarum</i> Q7. The effects of plantaricin Q7 on <i>Listeria monocytogenes</i> and its biofilm were investigated. The results showed that plantaricin Q7 changed the cell membrane permeability and integrity of <i>Listeria monocytogenes</i> significantly. The extracellular lactate dehydrogenase activity increased from 156.74 U/L to 497.62 U/L, and the K<sup>+</sup> concentration was increased rapidly from 0.02 g/L to 0.09 g/L. Furthermore, the flagellum motility of <i>Listeria monocytogenes</i> reduced and the relative adhesion rate decreased about 30% after treatment with plantaricin Q7. Meanwhile, the morphology and structure of <i>Listeria monocytogenes</i> cell and biofilm were damaged. These findings suggested that plantaricin Q7 exhibited significant inhibitory effects on not only <i>Listeria monocytogenes</i> cell but also its biofilm, which might be used as a natural and effective biological preservative for food storage.
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