Signet cell rectal carcinoma with prostatic involvement detected by FAPI-04 PET-MRI fusion

Abstract A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a complete metabolic response. After 6 months, CEA level...

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Bibliographic Details
Published in:European Journal of Hybrid Imaging
Main Authors: K. Arun Prashanth, Deepti Jain, R. Manikandan, Suman Kalyan, Vimalraj Velayutham, R. Surendran
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Subjects:
Signet cell adenocarcinoma
FAPI
Rectal adenocarcinoma
Prostate secondaries
FAPI MRI fusion
Fibroblast activation protein inhibitor PET-CT
Online Access:https://doi.org/10.1186/s41824-023-00183-4
Description
Summary:Abstract A 60-year-old male patient diagnosed with mucinous adenocarcinoma of lower third of rectum underwent abdominoperineal resection and permanent colostomy followed by adjuvant chemotherapy. Response evaluation with F-18 FDG PET-CT showed a complete metabolic response. After 6 months, CEA levels started increasing and clinically a recurrence was suspected. A restaging FDG PET-CT showed no obvious malignant disease. Patient presented again within a month with complaints of urinary retention and haematuria. CEA levels were further elevated, and Ga-68 FAPI-04 (FAPI) PET-CT was performed. FAPI PET-CT revealed prostatic and seminal vesicle disease involvement. Additionally, an MRI of pelvis was done and fused with FAPI PET for confirmation of prostatic involvement.
ISSN:2510-3636

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