Toxicological and therapeutic assessment of «Сoсtsidon suspension 5 %» at coccidiosis in pigs
Parameters of acute toxicity of «Сoсtsidon Suspension 5 %» are studied at in- jection: LD50 for mice made 23750±938,7 mg/kg, for rats - 28541,7±1666,1 mg/kg that gives the reason to assign this medicine to the 4th class of toxicity - low- dangerous drugs. Total dose of «Сoсtsidon Suspension 5 %» app...
| Published in: | Российский паразитологический журнал |
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| Main Authors: | , |
| Format: | Article |
| Language: | Russian |
| Published: |
Federal Scientific Centre VIEV
2016-05-01
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| Subjects: | |
| Online Access: | https://vniigis.elpub.ru/jour/article/view/225 |
| Summary: | Parameters of acute toxicity of «Сoсtsidon Suspension 5 %» are studied at in- jection: LD50 for mice made 23750±938,7 mg/kg, for rats - 28541,7±1666,1 mg/kg that gives the reason to assign this medicine to the 4th class of toxicity - low- dangerous drugs. Total dose of «Сoсtsidon Suspension 5 %» applied in the begin- ning of effect exceeded many times over the value of single dose LD50. In this con- nection, the cumulatively coefficient is much more than 1 that pointed at the lack of cumulative properties of a medicine. Efficiency of «Сoсtsidon Suspension 5 %» by coccidiosis in pigs made 100 %. At injection of medicine and within the next 30 days side-effects and complications are not detected |
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| ISSN: | 1998-8435 2541-7843 |