Integration of DOTA as a bridging unit during solid-phase peptide synthesis

A method for the introduction of bifunctionalized 1,4,7,10-tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid (DOTA) into the bridging unit of peptide-based radiopharmaceuticals has been developed. The method is executed in the context of Fmoc-based solid-phase peptide synthesis (SPPS) using stand...

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書誌詳細

出版年:	Results in Chemistry
主要な著者:	Lennard Wendlinger, Mara Parzinger, Margret Schottelius, Hans-Jürgen Wester
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-12-01
主題:	Chelator Bridging Unit Radiopharmaceuticals Solid-Phase Peptide Synthesis Radiohybrid Tracers
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211715623003156