An overview of RNA virus-encoded microRNAs

Abstract MicroRNAs (miRNAs) are a number of small non-coding RNAs playing a regulatory part in gene expression. Many virus-encoded miRNAs have been found, which manifests that viruses as well apply the basic pattern of gene regulation, however, mostly in viruses transcribed from double-stranded DNA...

詳細記述

書誌詳細
出版年:ExRNA
主要な著者: Xihan Li, Xiaoping Zou
フォーマット: 論文
言語:英語
出版事項: ELS Publishing (ELSP) 2019-10-01
オンライン・アクセス:http://link.springer.com/article/10.1186/s41544-019-0037-6
その他の書誌記述
要約:Abstract MicroRNAs (miRNAs) are a number of small non-coding RNAs playing a regulatory part in gene expression. Many virus-encoded miRNAs have been found, which manifests that viruses as well apply the basic pattern of gene regulation, however, mostly in viruses transcribed from double-stranded DNA genomes. It is still in dispute if RNA viruses could encode miRNAs because the excision of miRNA might result in the cleavage of viral RNA genome. We will focus on the miRNAs encoded by RNA virus and discuss their potential role in viral replication cycle and host cells.
ISSN:2398-0060