SNTA1-deficient human cardiomyocytes show shorter field potential duration and slower conduction velocity
Abstract In clinical settings, patients with α-1-syntrophin point mutations are often associated with rare arrhythmias, including Long QT syndrome, Brugada syndrome, and sudden infant death syndrome. Previous studies on α-1-syntrophin have predominantly utilized nonhuman cardiomyocyte models. This s...
| Published in: | Scientific Reports |
|---|---|
| Main Authors: | Tao Dong, Yan Zhao, Meng Zhang, Wei-Ya Lang, Dan-Yang Liu, Ke-Shuang Zhang, Yue-Jing Wang, Lin Li, Jie Lian, Hong-Bo Yao, Hai-Yan Zhang, Hai-Feng Jin, Tong Lu, Lei Shen, Li-Ling Yue, Yan Lin |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
|
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-16406-6 |
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