Prognostic value of tumor bulk in modern management of common lymphoma subtypes: an Australasian Lymphoma and Related Diseases Registry study

The presence of a single large disease site or so-called tumor ‘bulk’ in lymphoma has been variably associated with outcomes and influenced management decisions. However, challenges arise in using bulk as a prognosticator due to varied definitions across different lymphoma subtypes but also within...

Full description

Bibliographic Details
Published in:	Haematologica
Main Authors:	Eliza Chung, Luke Wang, Cameron Wellard, Allison Barraclough, Belinda A. Campbell, Geoffrey Chong, Pietro Di Ciaccio, Gareth P. Gregory, Greg Hapgood, Anna M. Johnston, Constantine S. Tam, Stephen Opat, Erica M. Wood, Zoe K. McQuilten, Eliza A. Hawkes
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2025-09-01
Online Access:	https://haematologica.org/article/view/12288

Similar Items

Definitions and use of tumor bulk in phase 3 lymphoma trials: a comprehensive literature review
by: Luke Wang, et al.
Published: (2025-05-01)

Body Mass Index and Clinical Associations in Australasian Lymphoma Patients: A Lymphoma and Related Diseases Registry Study
by: Serif Sungur, et al.
Published: (2026-04-01)

Impact and utility of follicular lymphoma GELF criteria in routine care: an Australasian Lymphoma Alliance study
by: Allison Barraclough, et al.
Published: (2024-03-01)

Real‐World Data on Lymphoma in Adolescents and Young Adults (AYA)—Report From the Lymphoma and Related Diseases Registry (LaRDR)
by: Evangeline Y. Wong, et al.
Published: (2025-02-01)

Outcomes in grade 3B follicular lymphoma: an international study led by the Australasian Lymphoma Alliance
by: Allison Barraclough, et al.
Published: (2023-02-01)

Management and Outcomes of Diffuse Large B-cell Lymphoma Post-transplant Lymphoproliferative Disorder in the Era of PET and Rituximab: A Multicenter Study From the Australasian Lymphoma Alliance
by: Stephen Boyle, et al.
Published: (2021-11-01)

Sequential high‐dose methotrexate and cytarabine administration improves outcomes in real‐world patients with primary central nervous system lymphoma: A report from the Australasian Lymphoma Alliance
by: Maciej Tatarczuch, et al.
Published: (2024-08-01)

Poor outcomes for trial‐ineligible patients receiving polatuzumab for relapsed/refractory diffuse large B‐cell lymphoma in routine care: An Australian Lymphoma and Related Diseases Registry project
by: Briony Shaw, et al.
Published: (2024-04-01)

P1193: POLATUZUMAB, BENDAMUSTINE & RITUXIMAB (POLA-BR) EFFICACY IN RELAPSED/REFRACTORY DIFFUSE LARGE B CELL LYMPHOMA (RRDLBCL) TRIAL-INELIGIBLE PATIENTS: AN AUSTRALIAN LYMPHOMA REGISTRY (LARDR) STUDY
by: Briony Shaw, et al.
Published: (2023-08-01)

P1127: FINAL ANALYSIS OF AUSTRALASIAN LEUKAEMIA & LYMPHOMA GROUP NHL29: A PHASE II STUDY OF IBRUTINIB, RITUXIMAB AND MINI-CHOP IN VERY ELDERLY PATIENTS WITH NEWLY DIAGNOSED DLBCL
by: Emma Verner, et al.
Published: (2023-08-01)

Lenalidomide Consolidation Added to Rituximab Maintenance Therapy in Patients Remaining PET Positive After Treatment for Relapsed Follicular Lymphoma: A Phase 2 Australasian Leukaemia & Lymphoma Group NHL26 Study
by: Judith Trotman, et al.
Published: (2023-03-01)

Outcomes of stage I/II follicular lymphoma in the PET era: an international study from the Australian Lymphoma Alliance
by: Joshua W.D. Tobin, et al.
Published: (2019-10-01)

T‐Cell Receptor Repertoires Show Dynamic Variation Between Diagnosis and Relapse of Diffuse Large B‐Cell Lymphoma
by: Joel Wight, et al.
Published: (2025-08-01)

PET/CT-derived coronary calcium score may predict cardiac complications in anthracycline-treated patients with lymphoma
by: Genevieve Douglas, et al.
Published: (2025-02-01)

Toxicity outcomes in phase 1 lymphoma trials abstracts are under‐reported, with high use of minimizing language
by: Marsali Maclean, et al.
Published: (2026-04-01)

Nivolumab and rituximab in treatment-naïve follicular lymphoma: the phase 2 1st FLOR study
by: Allison Barraclough, et al.
Published: (2025-03-01)

Dynamic Profiling of Cell Free Tumour DNA in Aggressive B‐Cell Lymphoma From Diagnosis to Transformation at Relapse
by: Mark Waltham, et al.
Published: (2025-08-01)

Australasian Religion Index (ARI)
by: Daniel Kolb
Published: (2008-11-01)

Opportunistic bone density assessment using pre-treatment [18F]FDG-PET/CT identifies fracture risk in lymphoma patients undergoing corticosteroid-containing chemotherapy
by: Genevieve Douglas, et al.
Published: (2025-01-01)

An Economic Evaluation of the TROG 99.03 Trial: Systemic Therapy After Radiotherapy in Early‐Stage Follicular Lymphoma
by: Daniel Erku, et al.
Published: (2025-02-01)

Platelet storage duration and its clinical and transfusion outcomes: a systematic review
by: Cécile Aubron, et al.
Published: (2018-08-01)

Venous thromboembolism in primary central nervous system lymphoma during frontline chemoimmunotherapy
by: Hiu Lam Agnes Yuen, et al.
Published: (2020-08-01)

A manifesto of panbiogeography, Australasian edition
by: David J. Lohman, et al.
Published: (2014-12-01)

Collaborative research in Australasian plastic surgery
by: Guy HM Stanley, et al.
Published: (2021-09-01)

Breeding Ewe Lambs: An Australasian Perspective
by: Paul R. Kenyon, et al.
Published: (2022-11-01)

T-cell dysregulation informs radiotherapy-immunotherapy response in B-cell lymphoma: results from a phase 1 trial
by: Eliza A. Hawkes, et al.
Published: (2025-10-01)

Allopatric speciation within a cryptic species complex of Australasian octopuses.
by: Michael D Amor, et al.
Published: (2014-01-01)

Targeted therapy in lymphoma
by: Cavalli Franco, et al.
Published: (2010-11-01)

Health-related quality of life in patients with indolent and aggressive non-Hodgkin lymphoma
by: Eliza M. Alawi, et al.
Published: (2016-12-01)

Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors
by: Sant-Rayn Pasricha, et al.
Published: (2011-08-01)

Comparison of the clinical characteristics of ovarian lymphoma and ovarian cancer with bulk lymph node involvement
by: 高菲菲, et al.
Published: (2017-05-01)

A decade of outcomes: The evolution of an australasian outcomes collaboration for chronic pain services
by: David Holloway, et al.
Published: (2023-04-01)

Tracing the tiger: population genetics provides valuable insights into the Aedes (Stegomyia) albopictus invasion of the Australasian Region.
by: Nigel W Beebe, et al.
Published: (2013-01-01)

P1230: T CELL CD62L EXPRESSION FOLLOWING NIVOLUMAB THERAPY IS ASSOCIATED WITH LONG TERM RESPONSE TO RITUXIMAB-NIVOLUMAB IN TREATMENT NAÏVE FOLLICULAR LYMPHOMA: RESULTS FROM THE 1ST FLOR STUDY
by: Rachel Koldej, et al.
Published: (2023-08-01)

Inflammatory Bowel Disease in Australasian Children and Adolescents
by: A. S. Day, et al.
Published: (2014-01-01)

Australasian Journal of Plastic Surgery: first edition
by: Mark Lee, et al.
Published: (2018-03-01)

Comparative diversity in glochidia of Australasian freshwater mussels
by: Michael W. Klunzinger, et al.
Published: (2023-12-01)

The Australasian Foundation for Plastic Surgery comes of age
by: Richard Barnett
Published: (2018-03-01)

Development of the 'Australasian' Woodland at Logan Botanic Garden
by: Barry Unwin
Published: (2005-10-01)

Australasian college of paramedicine international conference 2025
Published: (2026-01-01)