<i>Caesalpinia ferrea C. Mart.</i> (Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review

• 出版年: Molecules
• 主要な著者: Nair Silva Macêdo, Zildene de Sousa Silveira, Antonio Henrique Bezerra, José Galberto Martins da Costa, Henrique Douglas Melo Coutinho, Barbara Romano, Raffaele Capasso, Francisco Assis Bezerra da Cunha, Márcia Vanusa da Silva
• フォーマット: 論文
• 言語: 英語
• 出版事項: MDPI AG 2020-08-01
• 主題: <i>Caesalpinia ferrea</i>; ethnoknowledge; bioactivities; phytochemicals; HPLC
• オンライン･アクセス: https://www.mdpi.com/1420-3049/25/17/3831

<i>Caesalpinia ferrea C. Mart.</i>, popularly known as “Jucá” or “Pau-ferro”, belongs to the Fabaceae family, and is classified as a native and endemic species in Brazil. Numerous studies that portray its ethnobotany, chemical composition, and biological activities exist in the literature. The present study aimed to systematically review publications addressing the botanical aspects, uses in popular medicine, phytochemical composition, and bioactivities of <i>C. ferrea</i>. The searches focused on publications from 2015 to March 2020 using the Scopus, Periódicos Capes, PubMed, Google Scholar, and ScienceDirect databases. The leaves, fruits, seeds, and bark from <i>C. ferrea</i> are used in popular medicine to treat disorders affecting several systems, including the circulatory, immune, cardiovascular, digestive, respiratory, genitourinary, musculoskeletal, and conjunctive systems. The most commonly found chemical classes in phytochemical studies are flavonoids, polyphenols, terpenoids, tannins, saponins, steroids, and other phenolic compounds. The biological properties of the extracts and isolated compounds of <i>C. ferrea</i> most cited in the literature were antibacterial, antifungal, antioxidant, antiproliferative, anti-inflammatory, and healing potential. However, further studies are still needed to clarify a link between its traditional uses, the active compounds, and the reported pharmacological activities, as well as detailed research to determine the toxicological profile of <i>C. ferrea</i>.