Whole-blood model reveals granulocytes as key sites of dengue virus propagation, expanding understanding of disease pathogenesis
ABSTRACT Dengue virus (DENV) infection poses a significant global health threat, yet our understanding of its immunopathogenesis remains incomplete due to limitations of existing models. Here, we establish an in vitro whole-blood model using hirudin, an anticoagulant that preserves complement activi...
| 出版年: | mBio |
|---|---|
| 主要な著者: | Hansa Praneechit, Somchai Thiemmeca, Dararat Prayongkul, Kessiri Kongmanas, Dumrong Mairiang, Nuntaya Punyadee, Adisak Songjaeng, Nattaya Tangthawornchaikul, Nasikarn Angkasekwinai, Kanokwan Sriruksa, Yupin Suputtamongkol, Wannee Limpitikul, John P. Atkinson, Panisadee Avirutnan |
| フォーマット: | 論文 |
| 言語: | 英語 |
| 出版事項: |
American Society for Microbiology
2024-12-01
|
| 主題: | |
| オンライン･アクセス: | https://journals.asm.org/doi/10.1128/mbio.01505-24 |
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