Correlation between viral infections in male semen and infertility: a literature review
Abstract Infertility affects approximately one-sixth of couples globally, with the incidence of male infertility steadily increasing. However, our understanding of the impact of viral infections on fertility remains limited. This review consolidates findings from previous studies, outlining 40 virus...
| Published in: | Virology Journal |
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| Main Authors: | , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-07-01
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| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12985-024-02431-w |
| _version_ | 1850337614684487680 |
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| author | Yan Guo Yunhua Dong Runzi Zheng Jiacong Yan Weiyuan Li Ya Xu Xuelan Yan Yunmei Ke Yantao Li Lifeng Xiang |
| author_facet | Yan Guo Yunhua Dong Runzi Zheng Jiacong Yan Weiyuan Li Ya Xu Xuelan Yan Yunmei Ke Yantao Li Lifeng Xiang |
| author_sort | Yan Guo |
| collection | DOAJ |
| container_title | Virology Journal |
| description | Abstract Infertility affects approximately one-sixth of couples globally, with the incidence of male infertility steadily increasing. However, our understanding of the impact of viral infections on fertility remains limited. This review consolidates findings from previous studies, outlining 40 viruses identified in human semen and summarizing their key characteristics, modes of transmission, and their effects on both the reproductive and endocrine systems. Furthermore, it elucidates potential pathogenic mechanisms and treatment prospects of viruses strongly associated with male infertility. This synthesis will enhance our comprehension of how viral infections influence male reproductive health, offering valuable insights for future research as well as the diagnosis and treatment of infectious infertility. Graphical Abstract Abbreviated summary: Semen viral infections can damage the male reproductive system, further affecting semen quality and causing infertility, as well as sexually transmitted infections to partners and vertical transmission resulting in poor pregnancy outcomes. |
| format | Article |
| id | doaj-art-1d99276e95ec40d9be3bb604458205ec |
| institution | Directory of Open Access Journals |
| issn | 1743-422X |
| language | English |
| publishDate | 2024-07-01 |
| publisher | BMC |
| record_format | Article |
| spelling | doaj-art-1d99276e95ec40d9be3bb604458205ec2025-08-19T23:15:32ZengBMCVirology Journal1743-422X2024-07-0121111910.1186/s12985-024-02431-wCorrelation between viral infections in male semen and infertility: a literature reviewYan Guo0Yunhua Dong1Runzi Zheng2Jiacong Yan3Weiyuan Li4Ya Xu5Xuelan Yan6Yunmei Ke7Yantao Li8Lifeng Xiang9Department of Reproductive Gynecology, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Clinical Laboratory, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Gynecology, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Gynecology, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Gynecology, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceDepartment of Reproductive Medicine, NHC Key Laboratory of Healthy Birth and Birth Defect Prevention in Western China, the First People’s Hospital of Yunnan ProvinceAbstract Infertility affects approximately one-sixth of couples globally, with the incidence of male infertility steadily increasing. However, our understanding of the impact of viral infections on fertility remains limited. This review consolidates findings from previous studies, outlining 40 viruses identified in human semen and summarizing their key characteristics, modes of transmission, and their effects on both the reproductive and endocrine systems. Furthermore, it elucidates potential pathogenic mechanisms and treatment prospects of viruses strongly associated with male infertility. This synthesis will enhance our comprehension of how viral infections influence male reproductive health, offering valuable insights for future research as well as the diagnosis and treatment of infectious infertility. Graphical Abstract Abbreviated summary: Semen viral infections can damage the male reproductive system, further affecting semen quality and causing infertility, as well as sexually transmitted infections to partners and vertical transmission resulting in poor pregnancy outcomes.https://doi.org/10.1186/s12985-024-02431-wVirusSemenInfectionInfertilityReproductionSexual transmission |
| spellingShingle | Yan Guo Yunhua Dong Runzi Zheng Jiacong Yan Weiyuan Li Ya Xu Xuelan Yan Yunmei Ke Yantao Li Lifeng Xiang Correlation between viral infections in male semen and infertility: a literature review Virus Semen Infection Infertility Reproduction Sexual transmission |
| title | Correlation between viral infections in male semen and infertility: a literature review |
| title_full | Correlation between viral infections in male semen and infertility: a literature review |
| title_fullStr | Correlation between viral infections in male semen and infertility: a literature review |
| title_full_unstemmed | Correlation between viral infections in male semen and infertility: a literature review |
| title_short | Correlation between viral infections in male semen and infertility: a literature review |
| title_sort | correlation between viral infections in male semen and infertility a literature review |
| topic | Virus Semen Infection Infertility Reproduction Sexual transmission |
| url | https://doi.org/10.1186/s12985-024-02431-w |
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