Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium
Docosahexaenoic acid (DHA) is an n-3 polyunsaturated fatty acid that is essential for human nutrition. Currently, DHA is commonly produced using Aurantiochytrium, and omics technologies are widely used to investigate the mechanism underlying high DHA production in Aurantiochytrium, providing a found...
| Published in: | Shipin Kexue |
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| Main Author: | |
| Format: | Article |
| Language: | English |
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China Food Publishing Company
2024-07-01
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| Online Access: | https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-13-035.pdf |
| _version_ | 1849994923667881984 |
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| author | ZHANG Huaqiu, YANG Yingying, LIU Liping, YAO Mingjing, HAN Mo, ZHANG Jiaxiang, ZHAO Xiangying |
| author_facet | ZHANG Huaqiu, YANG Yingying, LIU Liping, YAO Mingjing, HAN Mo, ZHANG Jiaxiang, ZHAO Xiangying |
| author_sort | ZHANG Huaqiu, YANG Yingying, LIU Liping, YAO Mingjing, HAN Mo, ZHANG Jiaxiang, ZHAO Xiangying |
| collection | DOAJ |
| container_title | Shipin Kexue |
| description | Docosahexaenoic acid (DHA) is an n-3 polyunsaturated fatty acid that is essential for human nutrition. Currently, DHA is commonly produced using Aurantiochytrium, and omics technologies are widely used to investigate the mechanism underlying high DHA production in Aurantiochytrium, providing a foundation for genetic modification of Aurantiochytrium and control of the fermentation process. In this article, the history and major research directions of DHA production by Aurantiochytrium are summarized, and the application of omics technology in Aurantiochytrium is reviewed. It also summarizes recent progress in the application of genomics, transcriptomics, proteomics, metabolomics and multi-omics approaches as well as mathematical models based on omics data to reveal the mechanism underlying high DHA production in Aurantiochytrium. This review concludes with a discussion of future prospects for the development and application of omics technology. |
| format | Article |
| id | doaj-art-1e2ca04643dc45609bf7a4fbd29edc49 |
| institution | Directory of Open Access Journals |
| issn | 1002-6630 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | China Food Publishing Company |
| record_format | Article |
| spelling | doaj-art-1e2ca04643dc45609bf7a4fbd29edc492025-08-20T00:51:28ZengChina Food Publishing CompanyShipin Kexue1002-66302024-07-01451331232410.7506/spkx1002-6630-20230522-203Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by AurantiochytriumZHANG Huaqiu, YANG Yingying, LIU Liping, YAO Mingjing, HAN Mo, ZHANG Jiaxiang, ZHAO Xiangying0(1. Shandong Food Ferment Industry Research and Design Institute, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250013, China; 2. Department of Food Science and Engineering, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250013, China)Docosahexaenoic acid (DHA) is an n-3 polyunsaturated fatty acid that is essential for human nutrition. Currently, DHA is commonly produced using Aurantiochytrium, and omics technologies are widely used to investigate the mechanism underlying high DHA production in Aurantiochytrium, providing a foundation for genetic modification of Aurantiochytrium and control of the fermentation process. In this article, the history and major research directions of DHA production by Aurantiochytrium are summarized, and the application of omics technology in Aurantiochytrium is reviewed. It also summarizes recent progress in the application of genomics, transcriptomics, proteomics, metabolomics and multi-omics approaches as well as mathematical models based on omics data to reveal the mechanism underlying high DHA production in Aurantiochytrium. This review concludes with a discussion of future prospects for the development and application of omics technology.https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-13-035.pdfaurantiochytrium; genomics; transcriptomes; proteomics; metabolomics |
| spellingShingle | ZHANG Huaqiu, YANG Yingying, LIU Liping, YAO Mingjing, HAN Mo, ZHANG Jiaxiang, ZHAO Xiangying Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium aurantiochytrium; genomics; transcriptomes; proteomics; metabolomics |
| title | Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium |
| title_full | Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium |
| title_fullStr | Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium |
| title_full_unstemmed | Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium |
| title_short | Advances in the Application of Omics Technology in the Study of Docosahexaenic Acid Production by Aurantiochytrium |
| title_sort | advances in the application of omics technology in the study of docosahexaenic acid production by aurantiochytrium |
| topic | aurantiochytrium; genomics; transcriptomes; proteomics; metabolomics |
| url | https://www.spkx.net.cn/fileup/1002-6630/PDF/2024-45-13-035.pdf |
| work_keys_str_mv | AT zhanghuaqiuyangyingyingliulipingyaomingjinghanmozhangjiaxiangzhaoxiangying advancesintheapplicationofomicstechnologyinthestudyofdocosahexaenicacidproductionbyaurantiochytrium |