Synergistic anticancer effects of the 9.2.27PE immunotoxin and ABT-737 in melanoma.

In cancer, combinations of drugs targeting different cellular functions is well accepted to improve tumor control. We studied the effects of a Pseudomonas exotoxin A (PE)-based immunotoxin, the 9.2.27PE, and the BH-3 mimetic compound ABT-737 in a panel of melanoma cell lines. The drug combination re...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Karianne Risberg, Øystein Fodstad, Yvonne Andersson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Online Access:http://europepmc.org/articles/PMC3168478?pdf=render

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