Topical corticosteroids in combination with systemic acyclovir therapy in an atopic dermatitis patient with eczema herpeticum: A case report

Eczema herpeticum (EH), also known as Kaposi‘s varicelliform eruption, is a viral skin infection caused by the herpes simplex virus in the setting of compromised skin, most often associated with atopic dermatitis (AD). An eighteen-year-old female patient with a longstanding history of AD presented w...

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Bibliographic Details
Published in:Turkderm Turkish Archives of Dermatology and Venereology
Main Authors: Abdullah Demirbaş, Seda Dilek Yetut, Esin Diremsizoğlu
Format: Article
Language:English
Published: Society of Dermatology and Venereology 2025-09-01
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Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=turkderm&un=TURKDERM-54654
Description
Summary:Eczema herpeticum (EH), also known as Kaposi‘s varicelliform eruption, is a viral skin infection caused by the herpes simplex virus in the setting of compromised skin, most often associated with atopic dermatitis (AD). An eighteen-year-old female patient with a longstanding history of AD presented with EH, confirmed by viral testing, and was treated with intravenous acyclovir and topical antibiotics. A potent topical corticosteroid, clobetasol propionate, was applied to manage the underlying AD. Within five days, significant improvement was observed in both the viral and eczematous lesions with no adverse effects. This case highlights the effectiveness of combining antiviral therapy with topical corticosteroids in EH and the role of corticosteroids in supporting skin recovery in patients with AD at risk of EH.
ISSN:2651-5164