Utilization of Psychiatric Team Driven Ketamine Infusions
Introduction In 2018 Missouri University Psychiatric Center, an inpatient psychiatric hospital established a ketamine infusion team to treat severely depressed and acutely suicidal clients. Over 80 infusions were delivered over three years, with positive outcomes and minimal side effects. Objectiv...
| الحاوية / القاعدة: | European Psychiatry |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
Cambridge University Press
2022-06-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://www.cambridge.org/core/product/identifier/S0924933822014353/type/journal_article |
| الملخص: | Introduction
In 2018 Missouri University Psychiatric Center, an inpatient psychiatric hospital established a ketamine infusion team to treat severely depressed and acutely suicidal clients. Over 80 infusions were delivered over three years, with positive outcomes and minimal side effects.
Objectives
To evaluate outcomes of an inpatient psychiatric intravenous ketamine team to deliver treatment without anesthisia colloabration, which could open the horizon for future intravenous medications in a psychiatric inpatient setting.
Methods
A team consisting of a psychiatrist supported by a psychiatric PA, psychiatric pharmacist, and a mental health nurse devloped a protocol including physical and mental health screening, inclusion/exclusion criteria, dosing, and client monitoring. For data collection, the team monitored vital signs and mental status changes for tolerability and depression screening tools for efficacy.
Results
Table 1:
Ketamine Infusion Data
Total Clients
32
Male
15
Female
17
Dosing
0.5mg/kg adjusted bodyweight infused over 40 minutes
Average Baseline Depression Screening (PHQ or QIDS)*
20.8
Average Baseline Follow up Screening (PHQ or QIDS)*
7.5
Average Change in Screening Score (PHQ or QIDS)*
-14.1
% Change From Baseline in Screening Score (PHQ or QIDS)*
65.5%
Adverse Events Documented
Dissociation 5 (15.6%); Nausea/Vomiting 3 (.09%), Extreme Euphoria 2 (.06%); sedation 1 (.03%); BP Increase 1 (.03%)
Conclusions
Overall, ketamine infusions were tolerated well with limited adverse drugs reactions reported or observed and were easily addressed by the team without any serious adverse events. Given the rapid improvement of symptoms and overall tolerability, intravenous ketamine infusions conducted solely by a psychiatric-based team advances our field for further treament modalities.
Disclosure
No significant relationships.
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