| 總結: | ABSTRACT Thoracolumbar deformities related to spinal tumors or their treatments have emerged as a significant clinical challenge, primarily due to their impact on spinal stability, function, and patients’ quality of life. Structural changes may occur following tumor resection, radiotherapy, or chemotherapy, particularly in vulnerable populations such as children and adolescents. To analyze the risk factors, pathophysiological mechanisms, and preventive strategies associated with the development of thoracolumbar deformities during or after the treatment of spinal tumors. This narrative review is based on literature from the past three decades retrieved from the PubMed database. It includes original articles, systematic reviews, meta-analyses, and clinical guidelines addressing spinal instability, the biomechanical consequences of oncologic treatments, and preventive and therapeutic approaches. The development of spinal deformities is multifactorial, involving anatomical factors, patient age, extent of surgical resection, tumor location, and the adverse effects of radiotherapy and chemotherapy. Potential preventive strategies include laminoplasty, selective use of orthotic bracing, regular radiographic monitoring, and prophylactic spinal fusion, particularly in pediatric populations. The management of spinal tumors should extend beyond tumor resection to include measures aimed at preserving spinal biomechanics. Early identification of high-risk patients and the implementation of preventive strategies are essential to reducing the incidence of post-treatment deformities and improving functional outcomes. Level of Evidence IV; Case Series.
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