Preclinical Drug Response Metric Based on Cellular Response Phenotype Provides Better Pharmacogenomic Variables with Phenotype Relevance

High-throughput screening of drug response in cultured cell lines is essential for studying therapeutic mechanisms and identifying molecular variants associated with sensitivity to drugs. Assessment of drug response is typically performed by constructing a dose-response curve of viability and summar...

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發表在:	Pharmaceuticals
Main Authors:	Sanghyun Kim, Sohyun Hwang
格式:	Article
語言:	英语
出版:	MDPI AG 2021-12-01
主題:	high-throughput drug screening drug response metrics drug sensitivity metrics dose-response assessment
在線閱讀:	https://www.mdpi.com/1424-8247/14/12/1324