Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows

Subclinical hypocalcemia negatively impacts dairy cows’ health, milk production, and reproduction, posing a global challenge. This study evaluated the effects of aluminum sulfate supplementation in the close-up diet to reduce blood phosphorus levels and prevent postpartum hypocalcemia. Thirty-four c...

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Published in:Animals
Main Authors: Viktor Jurkovich, Mikolt Bakony, Per Theilgaard, Levente Kovács, Hedvig Fébel
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Subjects:
Online Access:https://www.mdpi.com/2076-2615/15/7/959
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author Viktor Jurkovich
Mikolt Bakony
Per Theilgaard
Levente Kovács
Hedvig Fébel
author_facet Viktor Jurkovich
Mikolt Bakony
Per Theilgaard
Levente Kovács
Hedvig Fébel
author_sort Viktor Jurkovich
collection DOAJ
container_title Animals
description Subclinical hypocalcemia negatively impacts dairy cows’ health, milk production, and reproduction, posing a global challenge. This study evaluated the effects of aluminum sulfate supplementation in the close-up diet to reduce blood phosphorus levels and prevent postpartum hypocalcemia. Thirty-four cows were assigned to the Control (CTRL, <i>n</i> = 17) and Treatment (TRT, <i>n</i> = 17) groups. The TRT group received 400 g/cow/day of aluminum sulfate at least 14 days before calving, with identical post-calving diets. Blood samples were analyzed for total and ionized calcium (tCa, iCa), phosphorus (P), magnesium (Mg), and beta-hydroxybutyrate (BHB). Milk yields were recorded. TRT cows had 0.22, 0.18, and 0.14 mmol/L higher tCa levels than CTRL cows at 12 h, 1 d, and 2 d postpartum, respectively, with elevated iCa levels from 10 days prepartum to 3 days postpartum. Lower serum P levels were observed in TRT cows until day 2 postpartum, while Mg levels remained similar. BHB levels differed only on day 14 postpartum. These findings suggest that aluminum sulfate supplementation effectively lowers serum P and increases tCa, offering a promising strategy for hypocalcemia prevention in dairy cows.
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spelling doaj-art-2bae423d4e3b4a5ba8715d74bfe73bef2025-08-20T03:08:43ZengMDPI AGAnimals2076-26152025-03-0115795910.3390/ani15070959Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy CowsViktor Jurkovich0Mikolt Bakony1Per Theilgaard2Levente Kovács3Hedvig Fébel4Centre for Animal Welfare, University of Veterinary Medicine, 1078 Budapest, HungaryCentre for Translational Medicine, Semmelweis University, 1085 Budapest, HungaryViloFoss, 7000 Fredericia, DenmarkInstitute of Animal Sciences, Hungarian University of Agriculture and Life Sciences, 2100 Gödöllő, HungaryDepartment of Obstetrics and Food Animal Medicine Clinic, University of Veterinary Medicine, 1078 Budapest, HungarySubclinical hypocalcemia negatively impacts dairy cows’ health, milk production, and reproduction, posing a global challenge. This study evaluated the effects of aluminum sulfate supplementation in the close-up diet to reduce blood phosphorus levels and prevent postpartum hypocalcemia. Thirty-four cows were assigned to the Control (CTRL, <i>n</i> = 17) and Treatment (TRT, <i>n</i> = 17) groups. The TRT group received 400 g/cow/day of aluminum sulfate at least 14 days before calving, with identical post-calving diets. Blood samples were analyzed for total and ionized calcium (tCa, iCa), phosphorus (P), magnesium (Mg), and beta-hydroxybutyrate (BHB). Milk yields were recorded. TRT cows had 0.22, 0.18, and 0.14 mmol/L higher tCa levels than CTRL cows at 12 h, 1 d, and 2 d postpartum, respectively, with elevated iCa levels from 10 days prepartum to 3 days postpartum. Lower serum P levels were observed in TRT cows until day 2 postpartum, while Mg levels remained similar. BHB levels differed only on day 14 postpartum. These findings suggest that aluminum sulfate supplementation effectively lowers serum P and increases tCa, offering a promising strategy for hypocalcemia prevention in dairy cows.https://www.mdpi.com/2076-2615/15/7/959aluminum sulfatedairy cowsionized calciumphosphorus bindingsubclinical hypocalcemiatotal calcium
spellingShingle Viktor Jurkovich
Mikolt Bakony
Per Theilgaard
Levente Kovács
Hedvig Fébel
Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows
aluminum sulfate
dairy cows
ionized calcium
phosphorus binding
subclinical hypocalcemia
total calcium
title Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows
title_full Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows
title_fullStr Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows
title_full_unstemmed Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows
title_short Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows
title_sort effects of a phosphorus binding feed supplement on the blood p and ca levels in dairy cows
topic aluminum sulfate
dairy cows
ionized calcium
phosphorus binding
subclinical hypocalcemia
total calcium
url https://www.mdpi.com/2076-2615/15/7/959
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