Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows
Subclinical hypocalcemia negatively impacts dairy cows’ health, milk production, and reproduction, posing a global challenge. This study evaluated the effects of aluminum sulfate supplementation in the close-up diet to reduce blood phosphorus levels and prevent postpartum hypocalcemia. Thirty-four c...
| Published in: | Animals |
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| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
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MDPI AG
2025-03-01
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| Online Access: | https://www.mdpi.com/2076-2615/15/7/959 |
| _version_ | 1849489638329155584 |
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| author | Viktor Jurkovich Mikolt Bakony Per Theilgaard Levente Kovács Hedvig Fébel |
| author_facet | Viktor Jurkovich Mikolt Bakony Per Theilgaard Levente Kovács Hedvig Fébel |
| author_sort | Viktor Jurkovich |
| collection | DOAJ |
| container_title | Animals |
| description | Subclinical hypocalcemia negatively impacts dairy cows’ health, milk production, and reproduction, posing a global challenge. This study evaluated the effects of aluminum sulfate supplementation in the close-up diet to reduce blood phosphorus levels and prevent postpartum hypocalcemia. Thirty-four cows were assigned to the Control (CTRL, <i>n</i> = 17) and Treatment (TRT, <i>n</i> = 17) groups. The TRT group received 400 g/cow/day of aluminum sulfate at least 14 days before calving, with identical post-calving diets. Blood samples were analyzed for total and ionized calcium (tCa, iCa), phosphorus (P), magnesium (Mg), and beta-hydroxybutyrate (BHB). Milk yields were recorded. TRT cows had 0.22, 0.18, and 0.14 mmol/L higher tCa levels than CTRL cows at 12 h, 1 d, and 2 d postpartum, respectively, with elevated iCa levels from 10 days prepartum to 3 days postpartum. Lower serum P levels were observed in TRT cows until day 2 postpartum, while Mg levels remained similar. BHB levels differed only on day 14 postpartum. These findings suggest that aluminum sulfate supplementation effectively lowers serum P and increases tCa, offering a promising strategy for hypocalcemia prevention in dairy cows. |
| format | Article |
| id | doaj-art-2bae423d4e3b4a5ba8715d74bfe73bef |
| institution | Directory of Open Access Journals |
| issn | 2076-2615 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| spelling | doaj-art-2bae423d4e3b4a5ba8715d74bfe73bef2025-08-20T03:08:43ZengMDPI AGAnimals2076-26152025-03-0115795910.3390/ani15070959Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy CowsViktor Jurkovich0Mikolt Bakony1Per Theilgaard2Levente Kovács3Hedvig Fébel4Centre for Animal Welfare, University of Veterinary Medicine, 1078 Budapest, HungaryCentre for Translational Medicine, Semmelweis University, 1085 Budapest, HungaryViloFoss, 7000 Fredericia, DenmarkInstitute of Animal Sciences, Hungarian University of Agriculture and Life Sciences, 2100 Gödöllő, HungaryDepartment of Obstetrics and Food Animal Medicine Clinic, University of Veterinary Medicine, 1078 Budapest, HungarySubclinical hypocalcemia negatively impacts dairy cows’ health, milk production, and reproduction, posing a global challenge. This study evaluated the effects of aluminum sulfate supplementation in the close-up diet to reduce blood phosphorus levels and prevent postpartum hypocalcemia. Thirty-four cows were assigned to the Control (CTRL, <i>n</i> = 17) and Treatment (TRT, <i>n</i> = 17) groups. The TRT group received 400 g/cow/day of aluminum sulfate at least 14 days before calving, with identical post-calving diets. Blood samples were analyzed for total and ionized calcium (tCa, iCa), phosphorus (P), magnesium (Mg), and beta-hydroxybutyrate (BHB). Milk yields were recorded. TRT cows had 0.22, 0.18, and 0.14 mmol/L higher tCa levels than CTRL cows at 12 h, 1 d, and 2 d postpartum, respectively, with elevated iCa levels from 10 days prepartum to 3 days postpartum. Lower serum P levels were observed in TRT cows until day 2 postpartum, while Mg levels remained similar. BHB levels differed only on day 14 postpartum. These findings suggest that aluminum sulfate supplementation effectively lowers serum P and increases tCa, offering a promising strategy for hypocalcemia prevention in dairy cows.https://www.mdpi.com/2076-2615/15/7/959aluminum sulfatedairy cowsionized calciumphosphorus bindingsubclinical hypocalcemiatotal calcium |
| spellingShingle | Viktor Jurkovich Mikolt Bakony Per Theilgaard Levente Kovács Hedvig Fébel Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows aluminum sulfate dairy cows ionized calcium phosphorus binding subclinical hypocalcemia total calcium |
| title | Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows |
| title_full | Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows |
| title_fullStr | Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows |
| title_full_unstemmed | Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows |
| title_short | Effects of a Phosphorus-Binding Feed Supplement on the Blood P and Ca Levels in Dairy Cows |
| title_sort | effects of a phosphorus binding feed supplement on the blood p and ca levels in dairy cows |
| topic | aluminum sulfate dairy cows ionized calcium phosphorus binding subclinical hypocalcemia total calcium |
| url | https://www.mdpi.com/2076-2615/15/7/959 |
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