Data in support of 5′AMP-activated protein kinase alpha regulates stress granule biogenesis
This data article contains insights into the regulation of cytoplasmic stress granules (SGs) by 5′-AMP-activated kinase (AMPK). Our results verify the specific association of AMPK-α2, but not AMPK-α1, with SGs. We also provide validation data for the isoform-specific recruitment of the AMPK-α subuni...
| Published in: | Data in Brief |
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| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2015-09-01
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352340915000529 |
| Summary: | This data article contains insights into the regulation of cytoplasmic stress granules (SGs) by 5′-AMP-activated kinase (AMPK). Our results verify the specific association of AMPK-α2, but not AMPK-α1, with SGs. We also provide validation data for the isoform-specific recruitment of the AMPK-α subunit to SGs using (i) different antibodies and (ii) a distinct cellular model system. In addition, we assess the SG association of the regulatory AMPK β- and γ-subunits. The interpretation of these data and further extensive insights into the regulation of SG biogenesis by AMPK can be found in “5′AMP-activated protein kinase alpha regulates stress granule biogenesis” [1]. |
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| ISSN: | 2352-3409 |