Role of NKCC1 and KCC2 during hypoxia-induced neuronal swelling in the neonatal neocortex

Neonatal hypoxia causes cytotoxic neuronal swelling by the entry of ions and water. Multiple water pathways have been implicated in neurons because these cells lack water channels, and their membrane has a low water permeability. NKCC1 and KCC2 are cation-chloride cotransporters (CCCs) involved in w...

Full description

Bibliographic Details
Published in:Neurobiology of Disease
Main Authors: Yusuke Takezawa, Rachel Langton, Samuel M. Baule, Miriam Bridget Zimmerman, Stephen Baek, Joseph Glykys
Format: Article
Language:English
Published: Elsevier 2023-03-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S096999612300027X

Similar Items