Adrenaline auto injectors pharmacokinetic/pharmacodynamic studies and potential consequences for clinical practice
Abstract Background Anaphylaxis is a sudden multisystem allergic reaction which may result in a fatal outcome if not treated promptly. Guidelines worldwide suggest intramuscular adrenaline as the first‐line treatment for anaphylaxis outside a perioperative reaction. Adrenaline autoinjectors (AAIs) a...
| Published in: | Clinical and Translational Allergy |
|---|---|
| Main Authors: | Margitta Worm, Adam T. Fox, Magnus Wickman, Johannes Ring, Motohiro Ebisawa, Guillaume Pouessel, Pete Smith |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-12-01
|
| Subjects: | |
| Online Access: | https://doi.org/10.1002/clt2.12323 |
Similar Items
Optimizing Adrenaline Administration in Anaphylaxis: Clinical Practice Considerations and Safety Insights
by: Motohiro Ebisawa, et al.
Published: (2025-08-01)
by: Motohiro Ebisawa, et al.
Published: (2025-08-01)
Improving adrenaline autoinjector adherence: A psychologically informed training for healthcare professionals
by: Béré Mahoney, et al.
Published: (2019-09-01)
by: Béré Mahoney, et al.
Published: (2019-09-01)
Food Allergy Management Competence in Greek Schools
by: Gavriela Feketea, et al.
Published: (2023-03-01)
by: Gavriela Feketea, et al.
Published: (2023-03-01)
Pediatric idiopathic anaphylaxis: practical management from infants to adolescents
by: Francesca Mori, et al.
Published: (2024-08-01)
by: Francesca Mori, et al.
Published: (2024-08-01)
Evaluation of adrenaline auto-injector prescription profiles: A population-based, retrospective cohort study within the National Insurance Claims Database of Japan
by: Sakura Sato, et al.
Published: (2022-07-01)
by: Sakura Sato, et al.
Published: (2022-07-01)
Is Switching of Adrenaline Auto Injector Devices a Concern for Anaphylaxis Management? A CROSS-Sectional Study
by: Caoimhe Cronin, et al.
Published: (2023-05-01)
by: Caoimhe Cronin, et al.
Published: (2023-05-01)
Global disparities in availability of epinephrine auto-injectors
by: Luciana Kase Tanno, MD, PhD, et al.
Published: (2023-10-01)
by: Luciana Kase Tanno, MD, PhD, et al.
Published: (2023-10-01)
Perspectives and gaps in the management of food allergy and anaphylaxis in the Asia-Pacific Region
by: Agnes Sze Yin Leung, MRCPCH, et al.
Published: (2024-05-01)
by: Agnes Sze Yin Leung, MRCPCH, et al.
Published: (2024-05-01)
Assessing the Knowledge of Anaphylaxis Management and Adrenaline Auto-Injector Administration among Parents of Children with Food Allergies: A Cross-Sectional Study
by: Caoimhe Cronin, et al.
Published: (2024-07-01)
by: Caoimhe Cronin, et al.
Published: (2024-07-01)
The pharmacokinetics of epinephrine/adrenaline autoinjectors
by: Sten Dreborg, et al.
Published: (2021-03-01)
by: Sten Dreborg, et al.
Published: (2021-03-01)
Adrenaline overdose in pediatric anaphylaxis: a case report
by: Pui Yi Lily Liew, et al.
Published: (2017-05-01)
by: Pui Yi Lily Liew, et al.
Published: (2017-05-01)
Anafilaksi, çocuk, besin alerjsi, adrenalin oto-enjektörü
by: Pınar Yılmazbaş, et al.
Published: (2021-05-01)
by: Pınar Yılmazbaş, et al.
Published: (2021-05-01)
Knowledge Levels of Pediatric Assistants on Anaphylaxis Management and Adrenaline Autoinjector Application Skills: Pretraining and Posttraining Evaluation
by: Ali Can Demirel, et al.
Published: (2022-09-01)
by: Ali Can Demirel, et al.
Published: (2022-09-01)
Repeated freezing to very low temperatures does not impact the amount ejected from EpiPen® and Jext® adrenaline autoinjectors
by: Felix N R Wood, et al.
Published: (2024-12-01)
by: Felix N R Wood, et al.
Published: (2024-12-01)
Adherence with epinephrine autoinjector prescriptions in primary care
by: Elissa M. Abrams, et al.
Published: (2017-11-01)
by: Elissa M. Abrams, et al.
Published: (2017-11-01)
10 practical priorities to prevent and manage serious allergic reactions: GA2LEN ANACare and EFA Anaphylaxis Manifesto
by: Antonella Muraro, et al.
Published: (2024-12-01)
by: Antonella Muraro, et al.
Published: (2024-12-01)
Orientation affects the integrity of glass ampoules of 1 in 1000 adrenaline on exposure to very low temperatures
by: Felix N. R. Wood, et al.
Published: (2024-12-01)
by: Felix N. R. Wood, et al.
Published: (2024-12-01)
An Evaluation of the Drone Delivery of Adrenaline Auto-Injectors for Anaphylaxis: Pharmacists’ Perceptions, Acceptance, and Concerns
by: September Beck, et al.
Published: (2020-10-01)
by: September Beck, et al.
Published: (2020-10-01)
Key considerations based on pharmacokinetic/pharmacodynamic in the design of antibody-drug conjugates
by: Yangyang Gao, et al.
Published: (2025-01-01)
by: Yangyang Gao, et al.
Published: (2025-01-01)
Pharmacokinetic–Pharmacodynamic Model for the Testosterone-Suppressive Effect of Leuprolide in Normal and Prostate Cancer Rats
by: Dong-Seok Lee, et al.
Published: (2018-04-01)
by: Dong-Seok Lee, et al.
Published: (2018-04-01)
Pharmacodynamics and pharmacokinetics of snake antivenom
by: Bhagya Nikapitiya, et al.
Published: (2018-06-01)
by: Bhagya Nikapitiya, et al.
Published: (2018-06-01)
Changes in anaphylaxis trends and characteristics in emergency department admissions in Türkiye: From 2015 to 2021 based on the Ministry of Health database
by: Elif Soyak Aytekin, MD, et al.
Published: (2025-01-01)
by: Elif Soyak Aytekin, MD, et al.
Published: (2025-01-01)
Pharmacodynamics and pharmacokinetics of nalbuphine in xylazine‑sedated horses
by: Amal Hammad, et al.
Published: (2023-05-01)
by: Amal Hammad, et al.
Published: (2023-05-01)
Diagnostic Dilemma in Allergy and Coronary Syndromes: Kounis Syndrome or Adrenaline Effect?
by: Ebru Atike Ongun, et al.
Published: (2018-04-01)
by: Ebru Atike Ongun, et al.
Published: (2018-04-01)
Pharmacokinetic/Pharmacodynamic Model of Neutropenia in Real-Life Palbociclib-Treated Patients
by: Alexandre Le Marouille, et al.
Published: (2021-10-01)
by: Alexandre Le Marouille, et al.
Published: (2021-10-01)
Exploring Apixaban Pharmacokinetics, Pharmacodynamics, and Safety in Hemodiafiltration Patients
by: Aurema Otero, et al.
Published: (2024-09-01)
by: Aurema Otero, et al.
Published: (2024-09-01)
Pharmacokinetic/pharmacodynamic comparison between generic and brand-name levofloxacin based on Monte Carlo simulation
by: Pan Ma, et al.
Published: (2023-06-01)
by: Pan Ma, et al.
Published: (2023-06-01)
Tigecycline Pharmacokinetic and Pharmacodynamic Profile in Patients with Chronic Obstructive Pulmonary Disease Exacerbation
by: Maria Kipourou, et al.
Published: (2023-02-01)
by: Maria Kipourou, et al.
Published: (2023-02-01)
Population Pharmacokinetic–Pharmacodynamic Analysis of a Reserpine-Induced Myalgia Model in Rats
by: Gloria M. Alfosea-Cuadrado, et al.
Published: (2024-08-01)
by: Gloria M. Alfosea-Cuadrado, et al.
Published: (2024-08-01)
The effects of rabeprazole on metformin pharmacokinetics and pharmacodynamics in Chinese healthy volunteers
by: Guojing Liu, et al.
Published: (2016-12-01)
by: Guojing Liu, et al.
Published: (2016-12-01)
EVALUATION OF ANAPHYLAXIS KNOWLEDGE LEVELS IN 4TH AND 5TH YEAR STUDENTS OF FACULTY OF DENTISTRY
by: Salih Düzgün, et al.
Published: (2025-07-01)
by: Salih Düzgün, et al.
Published: (2025-07-01)
Population Pharmacokinetics and Pharmacodynamics with Enterohepatic Recirculation of Co-Medication of Rosuvastatin and Ezetimibe
by: An H, et al.
Published: (2025-06-01)
by: An H, et al.
Published: (2025-06-01)
Pharmacokinetic and Pharmacodynamic Properties of Rosmarinic Acid in Rat Cholestatic Liver Injury
by: Jianbin Min, et al.
Published: (2018-09-01)
by: Jianbin Min, et al.
Published: (2018-09-01)
Influence of aprepitant on the pharmacodynamics and pharmacokinetics of gliclazide in rats and rabbits
by: Raghunandan Reddy Kura, et al.
Published: (2018-05-01)
by: Raghunandan Reddy Kura, et al.
Published: (2018-05-01)
Isavuconazole Pharmacokinetics and Pharmacodynamics in Children
by: Hirsh Elhence, et al.
Published: (2022-12-01)
by: Hirsh Elhence, et al.
Published: (2022-12-01)
COMPARISON OF PHARMACOKINETICS AND PHARMACODYNAMICS OF THE ORIGINAL AND GENERIC ENALAPRIL IN THE ELDERLY PATIENTS WITH ARTERIAL HYPERTENSION
by: O. P. Bobrova, et al.
Published: (2015-12-01)
by: O. P. Bobrova, et al.
Published: (2015-12-01)
Effects of Carbamazepine and Phenytoin on Pharmacokinetics and Pharmacodynamics of Rivaroxaban
by: Lien Thi Ngo, et al.
Published: (2020-10-01)
by: Lien Thi Ngo, et al.
Published: (2020-10-01)
Cinnamon modulates the pharmacodynamic & pharmacokinetic of amlodipine in hypertensive rats
by: Ibrahim Abdelsalam Abdelrahman, et al.
Published: (2023-09-01)
by: Ibrahim Abdelsalam Abdelrahman, et al.
Published: (2023-09-01)
The pharmacokinetics and pharmacodynamics of fentanyl administered via transdermal patch in horses
by: Rachel A. Reed, et al.
Published: (2024-03-01)
by: Rachel A. Reed, et al.
Published: (2024-03-01)
A semi-compartmental model describing the pharmacokinetic-pharmacodynamic relationship
by: Seunghee Ki
Published: (2020-01-01)
by: Seunghee Ki
Published: (2020-01-01)
Similar Items
-
Optimizing Adrenaline Administration in Anaphylaxis: Clinical Practice Considerations and Safety Insights
by: Motohiro Ebisawa, et al.
Published: (2025-08-01) -
Improving adrenaline autoinjector adherence: A psychologically informed training for healthcare professionals
by: Béré Mahoney, et al.
Published: (2019-09-01) -
Food Allergy Management Competence in Greek Schools
by: Gavriela Feketea, et al.
Published: (2023-03-01) -
Pediatric idiopathic anaphylaxis: practical management from infants to adolescents
by: Francesca Mori, et al.
Published: (2024-08-01) -
Evaluation of adrenaline auto-injector prescription profiles: A population-based, retrospective cohort study within the National Insurance Claims Database of Japan
by: Sakura Sato, et al.
Published: (2022-07-01)
