The role of Pazopanib in Soft Tissue Sarcoma: A comprehensive review of the literature

INTRODUCTION: Sarcomas are a rare and heterogeneous group of tumours of mesenchymal origin. Single agent pazopanib showed activity in a phase II clinical trial designed to screen various soft tissue sarcoma subtypes [10] and a phase III [11] clinical trial followed resulting in FDA approval in 2012...

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Bibliographic Details
Published in:Forum of Clinical Oncology
Main Authors: Fotopoulos George, Pentheroudakis George
Format: Article
Language:English
Published: Sciendo 2015-09-01
Subjects:
Online Access:https://doi.org/10.1515/fco-2015-0012
Description
Summary:INTRODUCTION: Sarcomas are a rare and heterogeneous group of tumours of mesenchymal origin. Single agent pazopanib showed activity in a phase II clinical trial designed to screen various soft tissue sarcoma subtypes [10] and a phase III [11] clinical trial followed resulting in FDA approval in 2012 for use in metastatic soft tissue sarcoma exposed to prior chemotherapy.
ISSN:1792-362X