IDH1 mutations in patients with myelodysplastic syndromes are associated with an unfavorable prognosis

Background Myelodysplastic syndromes are a heterogeneous group of hematopoietic stem cell disorders with a high propensity to transform into acute myeloid leukemia. Heterozygous missense mutations in IDH1 at position R132 and in IDH2 at positions R140 and R172 have recently been reported in acute my...

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Bibliographic Details

Published in:	Haematologica
Main Authors:	Felicitas Thol, Eva M. Weissinger, Jürgen Krauter, Katharina Wagner, Frederik Damm, Martin Wichmann, Gudrun Göhring, Christiane Schumann, Gesine Bug, Oliver Ottmann, Wolf-Karsten Hofmann, Brigitte Schlegelberger, Arnold Ganser, Michael Heuser
Format:	Article
Language:	English
Published:	Ferrata Storti Foundation 2010-10-01
Online Access:	https://haematologica.org/article/view/5750