miR-548d-3p Is Up-Regulated in Human Visceral Leishmaniasis and Suppresses Parasite Growth in Macrophages

Visceral leishmaniasis caused by Leishmania (Leishmania) infantum in Latin America progress with hepatosplenomegaly, pancytopenia, hypergammaglobulinemia, and weight loss and maybe lethal mainly in untreated cases. miRNAs are important regulators of immune and inflammatory gene expression, but their...

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Bibliographic Details
Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Eduardo Milton Ramos-Sanchez, Luiza Campos Reis, Marina de Assis Souza, Sandra Márcia Muxel, Kamila Reis Santos, Dimitris Lagos, Valéria Rêgo Alves Pereira, Maria Edileuza Felinto de Brito, Paul Martin Kaye, Lucile Maria Floeter-Winter, Hiro Goto
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-02-01
Subjects:	Leishmania (Leishmania) infantum microRNA visceral leishmaniasis THP-1 cells pathogenesis inflammation
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.826039/full

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