Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane Anesthesia

Infiltrative analgesia of the nasal cavity using a local anesthetic combined with a potent vasopressor like adrenaline is a well-accepted method for transnasal endoscopic approach in neurosurgeries under general anesthesia. The main purpose of vasoconstrictors in transnasal surgery is to cause blanc...

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Published in:Journal of Neuroanaesthesiology and Critical Care
Main Authors: Shweta S. Naik, Rohini M. Surve, Mathangi Krishnakumar
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2023-06-01
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1770774
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author Shweta S. Naik
Rohini M. Surve
Mathangi Krishnakumar
author_facet Shweta S. Naik
Rohini M. Surve
Mathangi Krishnakumar
author_sort Shweta S. Naik
collection DOAJ
container_title Journal of Neuroanaesthesiology and Critical Care
description Infiltrative analgesia of the nasal cavity using a local anesthetic combined with a potent vasopressor like adrenaline is a well-accepted method for transnasal endoscopic approach in neurosurgeries under general anesthesia. The main purpose of vasoconstrictors in transnasal surgery is to cause blanching of mucosa and reducing bleeding. Although it can reduce the systemic absorption and potential systemic toxicity of a local anesthetic, there can be systemic absorption of the vasoconstrictor itself. Desflurane can further potentiate the arrhythmogenicity of lignocaine with adrenaline by causing QTc prolongation. We report a case of transient ventricular tachycardia in a patient following nasal infiltration with lignocaine adrenaline under desflurane anesthesia.
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spelling doaj-art-2e2d90e22f764ff592f2d2ead640f2282025-08-20T00:56:25ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neuroanaesthesiology and Critical Care2348-05482348-926X2023-06-01100213213510.1055/s-0043-1770774Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane AnesthesiaShweta S. Naik0https://orcid.org/0000-0002-8341-9901Rohini M. Surve1https://orcid.org/0000-0002-5740-7122Mathangi Krishnakumar2https://orcid.org/0000-0002-9225-3165Department of Neuroanaesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, IndiaDepartment of Neuroanaesthesia and Neurocritical Care, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, IndiaDepartment of Anaesthesia and Critical Care, St John's Medical College Hospital, Bengaluru, Karnataka, IndiaInfiltrative analgesia of the nasal cavity using a local anesthetic combined with a potent vasopressor like adrenaline is a well-accepted method for transnasal endoscopic approach in neurosurgeries under general anesthesia. The main purpose of vasoconstrictors in transnasal surgery is to cause blanching of mucosa and reducing bleeding. Although it can reduce the systemic absorption and potential systemic toxicity of a local anesthetic, there can be systemic absorption of the vasoconstrictor itself. Desflurane can further potentiate the arrhythmogenicity of lignocaine with adrenaline by causing QTc prolongation. We report a case of transient ventricular tachycardia in a patient following nasal infiltration with lignocaine adrenaline under desflurane anesthesia.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1770774prolonged QTcdesfluraneadrenalineinfiltrationtransnasal surgery
spellingShingle Shweta S. Naik
Rohini M. Surve
Mathangi Krishnakumar
Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane Anesthesia
prolonged QTc
desflurane
adrenaline
infiltration
transnasal surgery
title Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane Anesthesia
title_full Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane Anesthesia
title_fullStr Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane Anesthesia
title_full_unstemmed Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane Anesthesia
title_short Ventricular Tachycardia after Submucosal Infiltration of Lignocaine 2% with Adrenaline in Endoscopic Pituitary Surgery Under Desflurane Anesthesia
title_sort ventricular tachycardia after submucosal infiltration of lignocaine 2 with adrenaline in endoscopic pituitary surgery under desflurane anesthesia
topic prolonged QTc
desflurane
adrenaline
infiltration
transnasal surgery
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1770774
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AT rohinimsurve ventriculartachycardiaaftersubmucosalinfiltrationoflignocaine2withadrenalineinendoscopicpituitarysurgeryunderdesfluraneanesthesia
AT mathangikrishnakumar ventriculartachycardiaaftersubmucosalinfiltrationoflignocaine2withadrenalineinendoscopicpituitarysurgeryunderdesfluraneanesthesia