WTAP Mediated m6A Modification Stabilizes PDIA3P1 and Promotes Tumor Progression Driven by Histone Lactylation in Esophageal Squamous Cell Carcinoma
Abstract Esophageal squamous cell carcinoma (ESCC) is a common digestive tract malignant cancer with high incidence and mortality rate. Many studies have shown that long noncoding RNAs (lncRNAs are involved in the progression of various types of tumors. The lncRNA protein disulfide isomerase family...
| 發表在: | Advanced Science |
|---|---|
| Main Authors: | Tao Huang, Qi You, Jiawei Liu, Xuguang Shen, Dengjun Huang, Xinlu Tao, Zhijie He, Chengwei Wu, Xinran Xi, Shouqiang Yu, Feng Liu, Zhihao Wu, Wenjun Mao, Shaojin Zhu |
| 格式: | Article |
| 語言: | 英语 |
| 出版: |
Wiley
2025-09-01
|
| 主題: | |
| 在線閱讀: | https://doi.org/10.1002/advs.202506529 |
相似書籍
Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells
由: Lianhong Pan, et al.
出版: (2022-07-01)
由: Lianhong Pan, et al.
出版: (2022-07-01)
Virus‐Induced Histone Lactylation Promotes Virus Infection in Crustacean
由: Yu Zhang, et al.
出版: (2024-08-01)
由: Yu Zhang, et al.
出版: (2024-08-01)
Demethylzeylasteral targets lactate to suppress the tumorigenicity of liver cancer stem cells: It is attributed to histone lactylation?
由: Hang Gong, et al.
出版: (2023-08-01)
由: Hang Gong, et al.
出版: (2023-08-01)
LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene
由: Junfeng Xia, et al.
出版: (2024-12-01)
由: Junfeng Xia, et al.
出版: (2024-12-01)
NCAPD3 contributes to lung cancer progression through modulated lactate-induced histone lactylation and MEK/ERK/LDHA axis
由: Zhibo Chang
出版: (2025-05-01)
由: Zhibo Chang
出版: (2025-05-01)
tsRNA-08614 inhibits glycolysis and histone lactylation by ALDH1A3 to confer oxaliplatin sensitivity in colorectal cancer
由: Zhengbo Chen, et al.
出版: (2025-08-01)
由: Zhengbo Chen, et al.
出版: (2025-08-01)
Lactylation and human disease
由: Linlin Wan, et al.
出版: (2025-01-01)
由: Linlin Wan, et al.
出版: (2025-01-01)
SIRT4 Promotes Pancreatic Cancer Stemness by Enhancing Histone Lactylation and Epigenetic Reprogramming Stimulated by Calcium Signaling
由: Mengzhu Lv, et al.
出版: (2025-05-01)
由: Mengzhu Lv, et al.
出版: (2025-05-01)
Histone Lactylation Participates in Psoriasis Progression by Regulating the Adiponectin Expression
由: Zhao S, et al.
出版: (2024-01-01)
由: Zhao S, et al.
出版: (2024-01-01)
Positive feedback regulation between glycolysis and histone lactylation drives oncogenesis in pancreatic ductal adenocarcinoma
由: Fei Li, et al.
出版: (2024-05-01)
由: Fei Li, et al.
出版: (2024-05-01)
Reply to the letter titled: Demethylzeylasteral targets lactate to suppress the tumorigenicity of liver cancer stem cells: Is it attributed to histone lactylation?
由: Chunli Wang, et al.
出版: (2023-08-01)
由: Chunli Wang, et al.
出版: (2023-08-01)
Histone lactylation-regulated METTL3 promotes ferroptosis via m6A-modification on ACSL4 in sepsis-associated lung injury
由: Dan Wu, et al.
出版: (2024-08-01)
由: Dan Wu, et al.
出版: (2024-08-01)
Gastrodin mitigates aortic valve calcification by inhibiting glycolysis and histone lactylation through interfering with valve interstitial cells
由: Yu Zhang, et al.
出版: (2025-06-01)
由: Yu Zhang, et al.
出版: (2025-06-01)
Glycolysis‐Histone Lactylation Crosstalk Drives TXNIP‐NLRP3‐Mediated PANoptosome Assembly and PANoptosis Activation Underlying Diabetic Retinopathy Pathogenesis
由: Xiaoting Xi, et al.
出版: (2025-09-01)
由: Xiaoting Xi, et al.
出版: (2025-09-01)
Urban airborne PM2.5 induces pulmonary fibrosis through triggering glycolysis and subsequent modification of histone lactylation in macrophages
由: Jingyi Li, et al.
出版: (2024-03-01)
由: Jingyi Li, et al.
出版: (2024-03-01)
PFKM‐Driven Lactate Overproduction Promotes Atrial Fibrillation via Triggering Cardiac Fibroblasts Histone Lactylation
由: Ning Fang, et al.
出版: (2025-09-01)
由: Ning Fang, et al.
出版: (2025-09-01)
Histone and non-histone lactylation: molecular mechanisms, biological functions, diseases, and therapeutic targets
由: Xia Peng, et al.
出版: (2025-06-01)
由: Xia Peng, et al.
出版: (2025-06-01)
Lactylation and antitumor immunity
由: Biao Yang, et al.
出版: (2025-10-01)
由: Biao Yang, et al.
出版: (2025-10-01)
Non-histone lactylation: unveiling its functional significance
由: Pusong Shi, et al.
出版: (2025-01-01)
由: Pusong Shi, et al.
出版: (2025-01-01)
Correction: Non-histone lactylation: unveiling its functional significance
由: Pusong Shi, et al.
出版: (2025-09-01)
由: Pusong Shi, et al.
出版: (2025-09-01)
Histone lactylation as a driver of metabolic reprogramming and immune evasion
由: Cai Qiaoting, et al.
出版: (2024-12-01)
由: Cai Qiaoting, et al.
出版: (2024-12-01)
Research progress and prospect of histone lactylation in digestive system tumors
由: ZENG Dandan, LUO Wenfeng, YE Jiazhou, LIN Yan, LIANG Rong
出版: (2025-04-01)
由: ZENG Dandan, LUO Wenfeng, YE Jiazhou, LIN Yan, LIANG Rong
出版: (2025-04-01)
Histone lactylation bridges metabolic reprogramming and epigenetic rewiring in driving carcinogenesis: Oncometabolite fuels oncogenic transcription
由: Yu Zhang, et al.
出版: (2024-03-01)
由: Yu Zhang, et al.
出版: (2024-03-01)
GLP-1R activation attenuates the progression of pulmonary fibrosis via disrupting NLRP3 inflammasome/PFKFB3-driven glycolysis interaction and histone lactylation
由: Chenyang Liu, et al.
出版: (2024-10-01)
由: Chenyang Liu, et al.
出版: (2024-10-01)
Lactate metabolism and histone lactylation in the central nervous system disorders: impacts and molecular mechanisms
由: Yao Wang, et al.
出版: (2024-11-01)
由: Yao Wang, et al.
出版: (2024-11-01)
The role and mechanism of histone lactylation in health and diseases
由: Yumei Xie, et al.
出版: (2022-08-01)
由: Yumei Xie, et al.
出版: (2022-08-01)
Histone Lactylation Antagonizes Senescence and Skeletal Muscle Aging by Modulating Aging‐Related Pathways
由: Fanju Meng, et al.
出版: (2025-06-01)
由: Fanju Meng, et al.
出版: (2025-06-01)
Epigenetic Modulation by Lactylation in Sepsis: Linking Metabolism to Immune Dysfunction
由: Chen Y, et al.
出版: (2025-06-01)
由: Chen Y, et al.
出版: (2025-06-01)
Interplay between metabolic reprogramming and post-translational modifications: from glycolysis to lactylation
由: Hengwei Wu, et al.
出版: (2023-06-01)
由: Hengwei Wu, et al.
出版: (2023-06-01)
Ubiquitous protein lactylation in health and diseases
由: Junyong Wang, et al.
出版: (2024-02-01)
由: Junyong Wang, et al.
出版: (2024-02-01)
H4K79 and H4K91 histone lactylation, newly identified lactylation sites enriched in breast cancer
由: Jiena Liu, et al.
出版: (2025-08-01)
由: Jiena Liu, et al.
出版: (2025-08-01)
Lactate and lysine lactylation of histone regulate transcription in cancer
由: Yunhao Yang, et al.
出版: (2024-11-01)
由: Yunhao Yang, et al.
出版: (2024-11-01)
Endothelial Cell‐Derived Lactate Triggers Bone Mesenchymal Stem Cell Histone Lactylation to Attenuate Osteoporosis
由: Jinhui Wu, et al.
出版: (2023-11-01)
由: Jinhui Wu, et al.
出版: (2023-11-01)
Hypoxia-induced PYCR1 regulates glycolysis and histone lactylation to promote bladder cancer progression and metastasis via SLC6A14/Glutamine metabolism
由: Zhuo Li, et al.
出版: (2025-12-01)
由: Zhuo Li, et al.
出版: (2025-12-01)
Histone Lactylation in Diseases: Regulation by Traditional Chinese Medicine and Therapeutic Implications
由: Qiu Y, et al.
出版: (2025-07-01)
由: Qiu Y, et al.
出版: (2025-07-01)
Lactylation-induced ALKBH5 targets RNF123 to worsen retinal Müller cell activation through PKM2-regulated Glycolysis in diabetic retinopathy
由: Shasha Luo, et al.
出版: (2025-10-01)
由: Shasha Luo, et al.
出版: (2025-10-01)
Gastrodin attenuates rheumatoid arthritis by targeting KAT8 to inhibit the lactylation of H3K9
由: Yufang Dai, et al.
出版: (2025-03-01)
由: Yufang Dai, et al.
出版: (2025-03-01)
Lactate promotes myogenesis via activating H3K9 lactylation‐dependent up‐regulation of Neu2 expression
由: Weilong Dai, et al.
出版: (2023-12-01)
由: Weilong Dai, et al.
出版: (2023-12-01)
Histone lactylation-boosted AURKB facilitates colorectal cancer progression by inhibiting HNRNPM-mediated PSAT1 mRNA degradation
由: Yuyi Li, et al.
出版: (2025-08-01)
由: Yuyi Li, et al.
出版: (2025-08-01)
Warburg effect and lactylation in cancer: mechanisms for chemoresistance
由: Wenjie Zhang, et al.
出版: (2025-04-01)
由: Wenjie Zhang, et al.
出版: (2025-04-01)
相似書籍
-
Demethylzeylasteral targets lactate by inhibiting histone lactylation to suppress the tumorigenicity of liver cancer stem cells
由: Lianhong Pan, et al.
出版: (2022-07-01) -
Virus‐Induced Histone Lactylation Promotes Virus Infection in Crustacean
由: Yu Zhang, et al.
出版: (2024-08-01) -
Demethylzeylasteral targets lactate to suppress the tumorigenicity of liver cancer stem cells: It is attributed to histone lactylation?
由: Hang Gong, et al.
出版: (2023-08-01) -
LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene
由: Junfeng Xia, et al.
出版: (2024-12-01) -
NCAPD3 contributes to lung cancer progression through modulated lactate-induced histone lactylation and MEK/ERK/LDHA axis
由: Zhibo Chang
出版: (2025-05-01)
